SCHEMBL6692014

SCHEMBL6692014

N#CC1CCCN1C(=O)CC(N)c1cc2ccccc2o1

nearest known ligand 0.53

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
PREP P48147 9/20 0.53
DPP4 P27487 9/20 0.52
DPP8 Q6V1X1 6/20 0.52
DPP7 Q9UHL4 3/20 0.51
DPP9 Q86TI2 1/20 0.51
FAP Q12884 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6685328 0.77 DPP4 (0.58) PREPDPP4DPP8DPP7DPP9
SCHEMBL6689349 0.76 DPP4 (0.52) PREPDPP4DPP8DPP7DPP9
SCHEMBL6693335 0.74 DPP4 (0.65) PREPDPP4DPP8DPP7DPP9
SCHEMBL6686202 0.74 DPP4 (0.61) PREPDPP4DPP8DPP7DPP9
SCHEMBL9045852 0.74 PREP (0.53) PREP
SCHEMBL6687279 0.74 DPP4 (0.50) PREPDPP4DPP8DPP7DPP9
SCHEMBL9045858 0.74 PREP (0.53) PREP
SCHEMBL9047445 0.74 PREP (0.74) PREP
SCHEMBL9047436 0.74 PREP (0.74) PREP
SCHEMBL6692186 0.73 DPP4 (0.62) PREPDPP4DPP8DPP7DPP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004089362-A1 2-CYANOPYRROLES AND THEIR ANALOGUES AS DDP-IV INHIBITORS NOVO NORDISK A/S (DK) 2004-10-21 WO disclosed