Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | CCR3 | P51677 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | CXCR3 | P49682 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | FSHR | P23945 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6687497 | 0.86 | MAPT (0.52) | MAPTCCR3LMNARAB9APOLB | |
| SCHEMBL29968689 | 0.86 | MAPT (0.52) | MAPTCCR3LMNARAB9APOLB | |
| SCHEMBL29968530 | 0.85 | MAPT (0.58) | MAPTLMNAPOLBTP53FSHR | |
| SCHEMBL6687109 | 0.85 | MAPT (0.58) | MAPTLMNAPOLBTP53FSHR | |
| SCHEMBL6690231 | 0.84 | MAPT (0.47) | MAPTLMNAPOLBCA1CA2 | |
| SCHEMBL29968850 | 0.84 | MAPT (0.47) | MAPTLMNAPOLBCA1CA2 | |
| SCHEMBL6687417 | 0.84 | MAPT (0.49) | MAPTCCR3LMNAPOLBCA1 | |
| SCHEMBL6684975 | 0.84 | NPSR1 (0.48) | MAPTLMNARAB9APOLBNPC1 | |
| SCHEMBL29968257 | 0.84 | NPSR1 (0.48) | MAPTLMNARAB9APOLBNPC1 | |
| SCHEMBL29968283 | 0.84 | MAPT (0.49) | MAPTCCR3LMNAPOLBCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004087685-A2 | PHOSPHOLIPASE C INHIBITORS FOR USE IN TREATING INFLAMMATORY DISORDERS | JANSSEN PHARMACEUTICA N.V. (BE) | 2004-10-14 | — | — | WO | claimed |