SCHEMBL6692833

SCHEMBL6692833

[CH2]SCCSC1CCCCC1

nearest known ligand 0.38

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
GBA1 P04062 3/20 0.38
ALDH1A1 P00352 3/20 0.35
RAB9A P51151 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
GAA P10253 1/20 0.35
SLC2A1 P11166 1/20 0.32
KMT2A Q03164 1/20 0.32
POLB P06746 2/20 0.31
NPC1 O15118 1/20 0.31
MDM2 Q00987 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL776553 0.87 GBA1 (0.44) GBA1ALDH1A1RAB9ASMN1; SMN2GAA
SCHEMBL2122298 0.77 GBA1 (0.39) GBA1ALDH1A1RAB9ASMN1; SMN2GAA
SCHEMBL8698883 0.77 GBA1 (0.39) GBA1ALDH1A1RAB9ASMN1; SMN2GAA
SCHEMBL8427828 0.76 GBA1 (0.36) GBA1ALDH1A1RAB9ASMN1; SMN2GAA
SCHEMBL6692837 0.75 GBA1 (0.38) GBA1ALDH1A1RAB9ASMN1; SMN2GAA
SCHEMBL8427539 0.75 GBA1 (0.35) GBA1ALDH1A1RAB9ASMN1; SMN2GAA
SCHEMBL27879167 0.75 GBA1 (0.35) GBA1ALDH1A1RAB9ASMN1; SMN2GAA
SCHEMBL6238509 0.74
SCHEMBL8429881 0.73 GBA1 (0.37) GBA1ALDH1A1RAB9ASMN1; SMN2GAA
SCHEMBL6612099 0.73 GBA1 (0.37) GBA1ALDH1A1RAB9ASMN1; SMN2GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0987567-B1 A sulfur-containing (thio)ether (co)polymer and a use thereof MITSUI CHEMICALS INC (JP) 2004-04-07 EP disclosed
US-6320020-B1 POLYMER OR COPOLYMER CONTAINING A SULFUR ATOM WHOSE PRINCIPAL BACKBONE COMPRISES ETHER AND/OR THIOETHER BONDS; OPTICAL DISK SUBSTRATE; A LIQUID-CRYSTAL PLASTIC SUBSTRATE; VARIOUS OPTICAL LENSES INCLUDING AN EYEGLASS; AND AN LED SEALING COAT. MITSUI CHEMICALS, INC. (JP) 2001-11-20 US disclosed
EP-0987567-A1 A sulfur-containing (thio)ether (co)polymer and a use thereof Mitsui Chemicals, Inc. (JP) 2000-03-22 EP disclosed