Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMT1 | P30419 | 1/20 | 0.55 |
| ▸ | SCN5A | Q14524 | 5/20 | 0.46 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.46 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.43 |
| ▸ | VSIR | Q9H7M9 | 1/20 | 0.43 |
| ▸ | PFKFB4 | Q16877 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | SCN1A | P35498 | 4/20 | 0.40 |
| ▸ | SCN8A | Q9UQD0 | 4/20 | 0.40 |
| ▸ | EIF2AK3 | Q9NZJ5 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3253473 | 0.79 | NMT1 (0.44) | NMT1SCN5ASCN9APIK3C3VSIR | |
| SCHEMBL3255842 | 0.77 | NMT1 (0.43) | NMT1SCN5ASCN9APIK3C3PFKFB4 | |
| SCHEMBL712317 | 0.76 | SCN9A (0.60) | NMT1SCN5ASCN9ASCN1ASCN8A | |
| SCHEMBL17154242 | 0.72 | SCN9A (0.51) | SCN5ASCN9ASCN1ASCN8ACYP2C9 | |
| SCHEMBL712535 | 0.71 | GAA (0.47) | SCN5ASCN9ALMNATSHRKMT2A | |
| SCHEMBL1853525 | 0.71 | NMT1 (1.00) | NMT1LMNAALOX15TSHR | |
| SCHEMBL2371748 | 0.71 | NMT1 (0.56) | NMT1PFKFB4EIF2AK3CYP3A4CYP2C9 | |
| SCHEMBL2372645 | 0.70 | NMT1 (0.56) | NMT1PIK3C3VSIRPFKFB4PPARG | |
| SCHEMBL6027408 | 0.70 | KDM4E (0.65) | NMT1PFKFB4LMNAKMT2A | |
| SCHEMBL1099422 | 0.69 | NMT1 (0.49) | NMT1PIK3C3VSIRPFKFB4PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004092123-A2 | INHIBITORS OF FUNGAL INVASION | MICROBIA, INC. (US) | 2004-10-28 | — | — | WO | disclosed |