Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.74 |
| ▸ | CA12 | O43570 | 1/20 | 0.59 |
| ▸ | CA1 | P00915 | 1/20 | 0.59 |
| ▸ | CA2 | P00918 | 1/20 | 0.59 |
| ▸ | CA9 | Q16790 | 1/20 | 0.59 |
| ▸ | EPHX1 | P07099 | 5/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | THRA | P10827 | 4/20 | 0.57 |
| ▸ | THRB | P10828 | 4/20 | 0.57 |
| ▸ | GHSR | Q92847 | 2/20 | 0.57 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.56 |
| ▸ | CNR1 | P21554 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6693240 | 1.00 | S1PR1 (0.74) | S1PR1CA12CA1CA2CA9 | |
| SCHEMBL6693150 | 1.00 | S1PR1 (0.74) | S1PR1CA12CA1CA2CA9 | |
| SCHEMBL6692687 | 1.00 | S1PR1 (0.74) | S1PR1CA12CA1CA2CA9 | |
| SCHEMBL6691078 | 1.00 | S1PR1 (0.74) | S1PR1CA12CA1CA2CA9 | |
| SCHEMBL6692988 | 0.99 | S1PR1 (0.71) | S1PR1CA12CA1CA2CA9 | |
| SCHEMBL6690275 | 0.87 | S1PR1 (0.56) | S1PR1EPHX1ALDH1A1CNR1SPHK1 | |
| SCHEMBL6690890 | 0.86 | CNR1 (0.57) | S1PR1EPHX1ALDH1A1CNR1 | |
| SCHEMBL6692401 | 0.86 | CNR1 (0.57) | S1PR1EPHX1ALDH1A1CNR1 | |
| SCHEMBL13267749 | 0.85 | S1PR1 (0.72) | S1PR1CA12CA1CA2CA9 | |
| SCHEMBL27855959 | 0.85 | S1PR1 (0.72) | S1PR1CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004106291-A1 | HALOETHYL UREA COMPOUNDS AND THE USE THEREOF TO ATTENUATE, INHIBIT OR PREVENT CANCER CELL MIGRATION | IMOTEP INC. (CA) | 2004-12-09 | — | — | WO | disclosed |
| WO-2004106292-A1 | HALOETHYL UREA COMPOUNDS AND THEIR USE TO ATTENUATE, INHIBIT OR PREVENT NON-CANCEROUS PATHOGENIC CELLULAR PROLIFERATION AND DISEASES ASSOCIATED THEREWITH | IMOTEP INC. (CA) | 2004-12-09 | — | — | WO | disclosed |