Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 11/20 | 0.43 |
| ▸ | S1PR3 | Q99500 | 7/20 | 0.43 |
| ▸ | PPARG | P37231 | 6/20 | 0.37 |
| ▸ | PPARA | Q07869 | 6/20 | 0.37 |
| ▸ | PPARD | Q03181 | 2/20 | 0.37 |
| ▸ | DAGLB | Q8NCG7 | 2/20 | 0.32 |
| ▸ | DAGLA | Q9Y4D2 | 2/20 | 0.32 |
| ▸ | DDHD2 | O94830 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4575948 | 0.85 | S1PR1 (0.41) | S1PR1S1PR3PPARGPPARAPPARD | |
| SCHEMBL4575973 | 0.70 | S1PR1 (0.41) | S1PR1S1PR3PPARGPPARAPPARD | |
| SCHEMBL4575979 | 0.70 | S1PR1 (0.41) | S1PR1S1PR3PPARGPPARAPPARD | |
| SCHEMBL4575562 | 0.66 | PPARA (0.41) | S1PR1S1PR3PPARGPPARAPPARD | |
| SCHEMBL4576077 | 0.66 | S1PR1 (0.43) | S1PR1S1PR3PPARGPPARAPPARD | |
| SCHEMBL16202249 | 0.65 | S1PR1 (0.79) | S1PR1S1PR3 | |
| Hydrochloric Acid SCHEMBL16143269 | 0.65 | S1PR1 (0.78) | S1PR1S1PR3 | |
| SCHEMBL14555386 | 0.64 | S1PR1 (0.61) | S1PR1S1PR3 | |
| SCHEMBL14555317 | 0.64 | S1PR1 (0.53) | S1PR1S1PR3 | |
| SCHEMBL7253896 | 0.63 | PPARA (0.49) | S1PR1S1PR3PPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1480957-A1 | HPPARS ACTIVATORS | SMITHKLINE BEECHAM CORPORATION (US) | 2004-12-01 | — | — | EP | disclosed |
| WO-2003074495-A1 | HPPARS ACTIVATORS | SMITHKLINE BEECHAM CORPORATION (US) | 2003-09-12 | — | — | WO | disclosed |