Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1653109 | 0.86 | F10 (0.80) | F10F2 | |
| SCHEMBL6696436 | 0.84 | F10 (0.72) | F10F2 | |
| SCHEMBL1654478 | 0.82 | F10 (0.75) | F10F2 | |
| SCHEMBL6698819 | 0.81 | F10 (0.68) | F10F2 | |
| SCHEMBL6997757 | 0.80 | F10 (0.66) | F10F2 | |
| SCHEMBL6698466 | 0.80 | F10 (1.00) | F10F2 | |
| SCHEMBL1652143 | 0.79 | F10 (0.76) | F10F2 | |
| SCHEMBL1654249 | 0.79 | F10 (0.69) | F10F2 | |
| SCHEMBL1651558 | 0.79 | F10 (0.73) | F10F2 | |
| SCHEMBL6698464 | 0.79 | F10 (0.70) | F10F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040072860-A1 | Piperazin-2-one amides as inhibitors of factor xa | MILLENNIUM PHARMACEUTICALS, INC. | 2004-04-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040072860-A1 | Piperazin-2-one amides as inhibitors of factor xa | F2, TFPI, TFPI2 | F10 12/4885F2 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.