Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRZ1 | P23471 | 3/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.41 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6693852 | 1.00 | PTPRZ1 (0.54) | PTPRZ1PTPN1PTPN2PTPN7MAOB | |
| SCHEMBL6687186 | 0.87 | MAOB (0.46) | PTPRZ1PTPN1PTPN2PTPN7MAOB | |
| SCHEMBL6688338 | 0.86 | MAOB (0.53) | MAOB | |
| SCHEMBL6688332 | 0.86 | MAOB (0.53) | MAOB | |
| SCHEMBL6688302 | 0.86 | PTPRZ1 (0.43) | PTPRZ1PTPN1PTPN2PTPN7PDCD1 | |
| SCHEMBL6688301 | 0.86 | PTPRZ1 (0.43) | PTPRZ1PTPN1PTPN2PTPN7PDCD1 | |
| SCHEMBL6691739 | 0.85 | CD274 (0.42) | PTPRZ1PDCD1CD274 | |
| SCHEMBL6691737 | 0.85 | CD274 (0.42) | PTPRZ1PDCD1CD274 | |
| SCHEMBL8935445 | 0.83 | BCHE (0.55) | MEN1POLBMAPK1KMT2ANPSR1 | |
| SCHEMBL3291152 | 0.83 | BCHE (0.55) | MEN1POLBMAPK1KMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004087125-A1 | AMINO ACID DERIVATIVES AS INHIBITORS OF MAMMALIAN SODIUM CHANNELS | IONIX PHARMACEUTICALS LIMITED (GB) | 2004-10-14 | — | — | WO | disclosed |