Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TRPV4 | Q9HBA0 | 12/20 | 0.40 |
| ▸ | ACLY | P53396 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2819901 | 0.83 | USP2 (0.48) | USP2CNR1MAPTTRPV4CYP3A4 | |
| SCHEMBL2821659 | 0.83 | USP2 (0.50) | USP2CNR1MAPTTRPV4CYP3A4 | |
| Hydrochloric Acid SCHEMBL2823513 | 0.82 | USP2 (0.47) | USP2CNR1MAPTTRPV4CYP3A4 | |
| Hydrochloric Acid SCHEMBL2823037 | 0.82 | USP2 (0.49) | USP2CNR1MAPTTRPV4CYP3A4 | |
| SCHEMBL2824037 | 0.76 | KMT2A (0.49) | USP2CNR1MAPTTRPV4TRPM8 | |
| SCHEMBL2823894 | 0.76 | USP2 (0.48) | USP2CNR1MAPTTRPV4CYP3A4 | |
| Hydrochloric Acid SCHEMBL2822124 | 0.76 | USP2 (0.47) | USP2CNR1MAPTTRPV4CYP3A4 | |
| SCHEMBL2820657 | 0.75 | USP2 (0.46) | USP2CNR1MAPTTRPV4CYP3A4 | |
| SCHEMBL2818819 | 0.75 | USP2 (0.46) | USP2CNR1MAPTTRPV4CYP3A4 | |
| SCHEMBL3836390 | 0.74 | USP2 (0.45) | USP2CNR1MAPTTRPV4CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1461038-A1 | ARYLSULFONAMIDE DERIVATIVES FOR USE AS CCR3 ANTAGONISTS IN THE TREATMENT OF INFLAMMATORY AND IMMUNOLOGICAL DISORDERS | Bayer HealthCare AG (DE) | 2004-09-29 | — | — | EP | claimed |
| WO-2003022277-A1 | ARYLSULFONAMIDE DERIVATIVES FOR USE AS CCR3 ANTAGONISTS IN THE TREATMENT OF INFLAMMATORY AND IMMUNOLOGICAL DISORDERS | BAYER HEALTHCARE AG (DE) | 2003-03-20 | — | — | WO | claimed |