Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.56 |
| ▸ | F10 | P00742 | 19/20 | 0.45 |
| ▸ | KLK1 | P06870 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6694012 | 1.00 | KCNH2 (0.56) | KCNH2F10KLK1 | |
| SCHEMBL6693782 | 0.93 | KCNH2 (0.49) | KCNH2F10 | |
| SCHEMBL6698024 | 0.90 | KCNH2 (0.61) | KCNH2F10KLK1 | |
| SCHEMBL6696815 | 0.87 | KCNH2 (0.55) | KCNH2F10KLK1 | |
| SCHEMBL6696811 | 0.87 | KCNH2 (0.55) | KCNH2F10KLK1 | |
| SCHEMBL6696721 | 0.85 | F10 (0.63) | KCNH2F10KLK1 | |
| SCHEMBL6694040 | 0.85 | KCNH2 (0.69) | KCNH2F10KLK1 | |
| SCHEMBL6698311 | 0.84 | F10 (0.57) | KCNH2F10 | |
| SCHEMBL6700838 | 0.84 | F10 (0.57) | KCNH2F10 | |
| SCHEMBL6697977 | 0.82 | KCNH2 (0.55) | KCNH2F10KLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040072860-A1 | Piperazin-2-one amides as inhibitors of factor xa | MILLENNIUM PHARMACEUTICALS, INC. | 2004-04-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040072860-A1 | Piperazin-2-one amides as inhibitors of factor xa | F2, TFPI, TFPI2 | KCNH2 2157/4885F10 12/4885KLK1 983/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.