Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | PLA2G7 | Q13093 | 2/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.38 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.38 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.37 |
| ▸ | EDNRB | P24530 | 1/20 | 0.37 |
| ▸ | EDNRA | P25101 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.35 |
| ▸ | CASP6 | P55212 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | JUN | P05412 | 1/20 | 0.34 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27685705 | 0.84 | ADORA2A (0.44) | CA2CA9ENPP3ADORA2AADORA1 | |
| SCHEMBL5692855 | 0.79 | EDNRB (0.44) | CA2CA9ENPP3ADORA2AADORA1 | |
| Hydrochloric Acid SCHEMBL5693359 | 0.78 | EDNRB (0.43) | CA2CA9ENPP3ADORA2AADORA1 | |
| SCHEMBL11211014 | 0.76 | PDPK1 (0.46) | ADORA2AADORA1PLA2G7PDPK1LOXL2 | |
| SCHEMBL1047236 | 0.76 | PDPK1 (0.53) | ADORA2AADORA1PLA2G7PDPK1LOXL2 | |
| SCHEMBL1093747 | 0.75 | ADORA2A (0.47) | CA2CA9ENPP3ADORA2AADORA1 | |
| SCHEMBL29608350 | 0.75 | ADORA2A (0.47) | CA2CA9ENPP3ADORA2AADORA1 | |
| Hydrochloric Acid SCHEMBL5692830 | 0.74 | ADORA2A (0.46) | CA2CA9ENPP3ADORA2AADORA1 | |
| Hydrochloric Acid SCHEMBL5692845 | 0.74 | ADORA2A (0.46) | CA2CA9ENPP3ADORA2AADORA1 | |
| SCHEMBL16180599 | 0.73 | ADORA2A (0.40) | CA2CA9ADORA2AADORA1HCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004112783-A1 | NEW USE IV | BIOVITRUM AB (SE) | 2004-12-29 | — | — | WO | claimed |