Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 16/20 | 0.39 |
| ▸ | MAPK13 | O15264 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1343509 | 0.91 | MAPK14 (0.45) | MAPK14MAPK13 | |
| SCHEMBL1341776 | 0.87 | NPC1 (0.38) | MAPK14MAPK13MAPT | |
| SCHEMBL6695971 | 0.86 | MAPK14 (0.39) | MAPK14MAPK13MAPT | |
| SCHEMBL6697886 | 0.86 | MAPK14 (0.41) | MAPK14MAPK13MAPT | |
| SCHEMBL1343743 | 0.86 | MAPK14 (0.34) | MAPK14MAPK13MAPT | |
| SCHEMBL2649931 | 0.84 | MAPK14 (0.40) | MAPK14MAPK13 | |
| SCHEMBL1340143 | 0.83 | NPC1 (0.36) | MAPT | |
| SCHEMBL6691983 | 0.83 | POLB (0.40) | MAPK14MAPK13MAPT | |
| SCHEMBL4475244 | 0.83 | MAPK14 (0.42) | MAPK14MAPK13 | |
| SCHEMBL1341599 | 0.82 | MAPK14 (0.40) | MAPK14MAPK13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040122235-A1 | Aryl carbonyl derivatives as therapeutic agents | VTV THERAPEUTICS LLC | 2004-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040122235-A1 | Aryl carbonyl derivatives as therapeutic agents | GCK, GCKR, PDK2 | MAPK14 1028/4885MAPK13 687/4885MAPT 2678/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.