Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.61 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | PDE4A | P27815 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | SLC6A6 | P31641 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 2/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.36 |
| ▸ | FAAH | O00519 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | NT5E | P21589 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA6 | P23280 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1271285 | 1.00 | APP (0.61) | APPPTGS1PDE4ALMNASLC6A6 | |
| SCHEMBL563101 | 1.00 | APP (0.61) | APPPTGS1PDE4ALMNASLC6A6 | |
| SCHEMBL28813930 | 1.00 | APP (0.61) | APPPTGS1PDE4ALMNASLC6A6 | |
| SCHEMBL1270769 | 1.00 | APP (0.61) | APPPTGS1PDE4ALMNASLC6A6 | |
| SCHEMBL922126 | 1.00 | APP (0.61) | APPPTGS1PDE4ALMNASLC6A6 | |
| SCHEMBL563945 | 1.00 | APP (0.61) | APPPTGS1PDE4ALMNASLC6A6 | |
| SCHEMBL1270542 | 1.00 | APP (0.61) | APPPTGS1PDE4ALMNASLC6A6 | |
| SCHEMBL6692218 | 1.00 | APP (0.61) | APPPTGS1PDE4ALMNASLC6A6 | |
| SCHEMBL1270406 | 1.00 | APP (0.61) | APPPTGS1PDE4ALMNASLC6A6 | |
| SCHEMBL1270555 | 1.00 | APP (0.61) | APPPTGS1PDE4ALMNASLC6A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004096977-A2 | CRYSTAL STRUCTURE OF HOMO SAPIENS ADIPOCYTE LIPID BINDING PROTEIN AND USES THEREOF | PFIZER PRODUCTS INC. (US) | 2004-11-11 | — | — | WO | claimed |
| US-20040219653-A1 | Crystal structure of homo sapiens adipocyte lipid binbing protein and uses thereof | PFIZER INC | 2004-11-04 | — | — | US | claimed |
| WO-2004096977-A2 | CRYSTAL STRUCTURE OF HOMO SAPIENS ADIPOCYTE LIPID BINDING PROTEIN AND USES THEREOF | PFIZER PRODUCTS INC. (US) | 2004-11-11 | — | — | WO | disclosed |
| US-20040219653-A1 | Crystal structure of homo sapiens adipocyte lipid binbing protein and uses thereof | PFIZER INC | 2004-11-04 | — | — | US | disclosed |