SCHEMBL6695979

SCHEMBL6695979

CCCCCCc1ccc(NC(=O)NCC(C)Cl)cc1

nearest known ligand 0.64

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
S1PR1 P21453 1/20 0.64
SPHK1 Q9NYA1 10/20 0.57
CA12 O43570 1/20 0.57
CA1 P00915 1/20 0.57
CA2 P00918 1/20 0.57
CA9 Q16790 1/20 0.57
THRA P10827 3/20 0.56
THRB P10828 3/20 0.56
EPHX1 P07099 2/20 0.55
EPHX2 P34913 1/20 0.55
GAA P10253 1/20 0.54
NPC1 O15118 1/20 0.53
RAB9A P51151 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
SPHK2 Q9NRA0 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13267749 0.84 S1PR1 (0.72) S1PR1SPHK1CA12CA1CA2
SCHEMBL27855959 0.84 S1PR1 (0.72) S1PR1SPHK1CA12CA1CA2
SCHEMBL11353893 0.84 CA12 (0.76) S1PR1SPHK1CA12CA1CA2
SCHEMBL15093429 0.84 CA12 (0.76) S1PR1SPHK1CA12CA1CA2
SCHEMBL27905675 0.84 CA12 (0.76) S1PR1SPHK1CA12CA1CA2
SCHEMBL11349336 0.84 CA12 (0.76) S1PR1SPHK1CA12CA1CA2
SCHEMBL15093871 0.84 CA12 (0.76) S1PR1SPHK1CA12CA1CA2
SCHEMBL11361435 0.84 CA12 (0.76) S1PR1SPHK1CA12CA1CA2
SCHEMBL11352018 0.84 CA12 (0.76) S1PR1SPHK1CA12CA1CA2
SCHEMBL15094111 0.84 CA12 (0.76) S1PR1SPHK1CA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004106291-A1 HALOETHYL UREA COMPOUNDS AND THE USE THEREOF TO ATTENUATE, INHIBIT OR PREVENT CANCER CELL MIGRATION IMOTEP INC. (CA) 2004-12-09 WO disclosed