⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7164244 | 0.88 | — | — | |
| SCHEMBL6699582 | 0.88 | — | — | |
| Trifluoroacetic Acid SCHEMBL6695744 | 0.83 | — | — | |
| SCHEMBL6697665 | 0.77 | — | — | |
| SCHEMBL6693444 | 0.76 | — | — | |
| SCHEMBL6699662 | 0.76 | — | — | |
| SCHEMBL6693733 | 0.72 | — | — | |
| SCHEMBL6694304 | 0.72 | — | — | |
| SCHEMBL7169132 | 0.72 | — | — | |
| SCHEMBL7170130 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6831096-B2 | Effective against both A and B forms of influenza; oral bioavailability | ABBOTT LABORATORIES | 2004-12-14 | — | — | US | disclosed |
| US-20040097471-A1 | Inhibitors of neuraminidases | ABBVIE INC. | 2004-05-20 | — | — | US | disclosed |
| EP-1358154-A2 | PYRROLIDINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS INHIBITORS OF NEURAMINIDASES | Abbott Laboratories (US) | 2003-11-05 | — | — | EP | disclosed |
| WO-2001028996-A2 | PYRROLIDINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS INHIBITORS OF NEURAMINIDASES | ABBOTT LABORATORIES (US) | 2001-04-26 | — | — | WO | disclosed |