Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 19/20 | 0.83 |
| ▸ | KDR | P35968 | 8/20 | 0.71 |
| ▸ | FYN | P06241 | 7/20 | 0.71 |
| ▸ | YES1 | P07947 | 7/20 | 0.71 |
| ▸ | PDGFRB | P09619 | 7/20 | 0.71 |
| ▸ | FGFR1 | P11362 | 7/20 | 0.71 |
| ▸ | LCK | P06239 | 6/20 | 0.71 |
| ▸ | AURKA | O14965 | 1/20 | 0.63 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.63 |
| ▸ | EGFR | P00533 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6697982 | 0.92 | SRC (0.98) | SRCKDRFYNYES1PDGFRB | |
| SCHEMBL6694710 | 0.91 | SRC (0.80) | SRCKDRFYNYES1PDGFRB | |
| SCHEMBL6692331 | 0.90 | SRC (0.82) | SRCKDRFYNYES1PDGFRB | |
| SCHEMBL6696417 | 0.89 | SRC (0.80) | SRCKDRFYNYES1PDGFRB | |
| SCHEMBL6695441 | 0.86 | SRC (0.82) | SRCKDRFYNYES1PDGFRB | |
| SCHEMBL6619232 | 0.85 | SRC (0.83) | SRCKDRFYNYES1PDGFRB | |
| SCHEMBL6701340 | 0.84 | SRC (0.98) | SRCKDRFYNYES1PDGFRB | |
| SCHEMBL6692307 | 0.84 | SRC (0.98) | SRCKDRFYNYES1PDGFRB | |
| SCHEMBL6616013 | 0.84 | SRC (0.86) | SRCKDRFYNYES1PDGFRB | |
| SCHEMBL6696870 | 0.83 | SRC (0.77) | SRCKDRFYNYES1PDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040186160-A1 | Hexahydro-cyclohepta-pyrrole oxindole as potent kinase inhibitors | SUGEN, INC. | 2004-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040186160-A1 | Hexahydro-cyclohepta-pyrrole oxindole as potent kinase inhibitors | MAP3K15, MAP3K20, MAP3K19 | SRC 162/4885KDR 749/4885FYN 137/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.