Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMO | Q99835 | 3/20 | 0.45 |
| ▸ | S1PR1 | P21453 | 6/20 | 0.43 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | LYN | P07948 | 1/20 | 0.41 |
| ▸ | HCK | P08631 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | MTTP | P55157 | 4/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | APOB | P04114 | 1/20 | 0.39 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6919444 | 0.91 | SMO (0.54) | SMOMTTPAPOB | |
| Hydrochloric Acid SCHEMBL6668967 | 0.84 | HDAC1 (0.46) | SMOS1PR1S1PR3SORT1 | |
| SCHEMBL6668413 | 0.83 | S1PR1 (0.45) | SMOS1PR1S1PR3SORT1HRH1 | |
| SCHEMBL6667324 | 0.82 | SMO (0.45) | SMOS1PR1S1PR3SORT1TRPV4 | |
| SCHEMBL6665670 | 0.79 | S1PR1 (0.48) | S1PR1S1PR3 | |
| SCHEMBL6801109 | 0.79 | SMO (0.47) | SMOS1PR1S1PR3MTTPHRH1 | |
| SCHEMBL6639807 | 0.78 | SMO (0.49) | SMOSORT1LCKLYNHCK | |
| SCHEMBL7087226 | 0.77 | SMO (0.49) | SMOSORT1KDR | |
| SCHEMBL6666013 | 0.77 | SMO (0.51) | SMOS1PR1S1PR3SORT1MTTP | |
| SCHEMBL6666524 | 0.77 | SMO (0.51) | SMOS1PR1S1PR3SORT1MTTP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1383760-A1 | BIARYLCARBOXAMIDE COMPOUNDS AS APOLIPOPROTEIN B INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-01-28 | — | — | EP | disclosed |
| WO-2002090347-A1 | AMIDE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-14 | — | — | WO | disclosed |