Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | ANPEP | P15144 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | ATM | Q13315 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6696413 | 1.00 | USP2 (0.56) | USP2ANPEPALDH1A1KDM4EMEN1 | |
| SCHEMBL6696422 | 1.00 | USP2 (0.56) | USP2ANPEPALDH1A1KDM4EMEN1 | |
| SCHEMBL372508 | 0.86 | USP2 (0.58) | USP2ANPEPALDH1A1KDM4EMEN1 | |
| SCHEMBL3954978 | 0.78 | USP2 (0.50) | USP2ANPEPALDH1A1KDM4EMEN1 | |
| SCHEMBL6505664 | 0.77 | USP2 (0.67) | USP2ANPEPALDH1A1KDM4EMEN1 | |
| SCHEMBL14440763 | 0.77 | MAPT (0.54) | ANPEPALDH1A1MEN1KMT2AHSD17B10 | |
| SCHEMBL17955613 | 0.77 | USP2 (0.60) | USP2ANPEPALDH1A1KDM4EMEN1 | |
| SCHEMBL5076673 | 0.77 | USP2 (0.48) | USP2ANPEPALDH1A1KDM4EMEN1 | |
| SCHEMBL17819447 | 0.77 | USP2 (0.48) | USP2ANPEPALDH1A1KDM4EMEN1 | |
| SCHEMBL4201455 | 0.77 | USP2 (0.58) | USP2ANPEPALDH1A1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040186160-A1 | Hexahydro-cyclohepta-pyrrole oxindole as potent kinase inhibitors | SUGEN, INC. | 2004-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040186160-A1 | Hexahydro-cyclohepta-pyrrole oxindole as potent kinase inhibitors | MAP3K15, MAP3K20, MAP3K19 | USP2 1332/4885ANPEP 2129/4885ALDH1A1 3282/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.