⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28099649 | 0.71 | — | — | |
| SCHEMBL8415036 | 0.61 | — | — | |
| SCHEMBL1133633 | 0.61 | — | — | |
| SCHEMBL9823299 | 0.60 | — | — | |
| SCHEMBL27976722 | 0.58 | — | — | |
| SCHEMBL27723749 | 0.58 | TSHR (0.41) | — | |
| SCHEMBL30457686 | 0.57 | — | — | |
| SCHEMBL19750859 | 0.57 | TSHR (0.35) | — | |
| SCHEMBL25336705 | 0.57 | — | — | |
| SCHEMBL3921585 | 0.57 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040234619-A1 | Methods for remodeling neuronal and cardiovascular pathways | CELLEGY PHARMACEUTICALS, INC. | 2004-11-25 | — | — | US | disclosed |
| US-6787553-B2 | SEXUAL DISORDERS; VASODILATION | CELLEGY PHARMACEUTICALS, INC. | 2004-09-07 | — | — | US | disclosed |
| US-20040138291-A1 | Treatment of sexual dysfunction | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2004-07-15 | — | — | US | disclosed |
| US-20040063719-A1 | Combination therapy using antihypertensive agents and endothelin antagonists | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2004-04-01 | — | — | US | disclosed |
| US-20030008020-A1 | Methods for remodeling neuronal and cardiovascular pathways | QUEEN'S UNIVERSITY OF KINGSTON (CA) | 2003-01-09 | — | — | US | disclosed |
| US-6458797-B1 | IN ILIO-HYPOGASTRIC-PUDENDAL ARTERIAL BED AND GENITALIA BY ADMINISTERING TO HUMANS THERAPEUTICALLY EFFECTIVE AMOUNT OF ANTI-PRESSOR AGENT | QUEEN'S UNIVERSITY OF KINGSTON (CA) | 2002-10-01 | — | — | US | disclosed |
| US-20020035067-A1 | Methods for remodeling neuronal and cardiovascular pathways | CELLEGY PHARMACEUTICALS, INC. | 2002-03-21 | — | — | US | disclosed |
| US-20020022587-A1 | Methods for effecting neuroprotection | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2002-02-21 | — | — | US | disclosed |
| WO-2001072335-A2 | METHODS FOR EFFECTING NEUROPROTECTION USING A POTASSIUM CHANNEL MODULATOR | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2001-10-04 | — | — | WO | disclosed |
| US-6284763-B1 | ADMINISTERING LOW DOSAGE OF ANTIPRESSOR AGENT | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2001-09-04 | — | — | US | disclosed |