SCHEMBL6699487

SCHEMBL6699487

O=CC=CCc1ccc2c(c1)OCO2

nearest known ligand 0.60

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 5/20 0.60
CYP1A2 P05177 2/20 0.60
MAPT P10636 1/20 0.60
CMA1 P23946 1/20 0.53
TAAR1 Q96RJ0 3/20 0.49
ALDH1A1 P00352 4/20 0.47
CYP2C19 P33261 1/20 0.47
SLC6A4 P31645 2/20 0.47
TDP1 Q9NUW8 2/20 0.47
HSD17B10 Q99714 2/20 0.47
KMT2A Q03164 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
DPP7 Q9UHL4 1/20 0.46
SLC6A2 P23975 1/20 0.45
SLC6A3 Q01959 1/20 0.45
CYP2D6 P10635 1/20 0.45
GAA P10253 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6699486 1.00 CYP3A4 (0.60) CYP3A4CYP1A2MAPTCMA1TAAR1
SCHEMBL30194501 0.84 CYP3A4 (0.70) CYP3A4CYP1A2MAPTCMA1TAAR1
SCHEMBL406700 0.84 CYP3A4 (0.70) CYP3A4CYP1A2MAPTCMA1TAAR1
SCHEMBL27523332 0.83 CYP3A4 (0.64) CYP3A4CYP1A2MAPTCMA1TAAR1
Propane SCHEMBL7426260 0.79 CYP3A4 (0.64) CYP3A4CYP1A2MAPTCMA1TAAR1
SCHEMBL10421649 0.79 CYP3A4 (0.64) CYP3A4CYP1A2MAPTCMA1TAAR1
SCHEMBL13841272 0.79 CYP3A4 (0.64) CYP3A4CYP1A2MAPTCMA1TAAR1
SCHEMBL29373539 0.78 CYP3A4 (0.57) CYP3A4CYP1A2MAPTALDH1A1CYP2C19
SCHEMBL2876933 0.78 CYP3A4 (0.57) CYP3A4CYP1A2MAPTALDH1A1CYP2C19
SCHEMBL2876936 0.78 CYP3A4 (0.57) CYP3A4CYP1A2MAPTALDH1A1CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2004269376-A METHOD FOR PRODUCING 1-FORMYL-3-(3,4-METHYLENEDIOXYPHENYL)PROPENE DERIVATIVE UBE IND LTD 2004-09-30 JP disclosed
JP-2004269376-A METHOD FOR PRODUCING 1-FORMYL-3-(3,4-METHYLENEDIOXYPHENYL)PROPENE DERIVATIVE UBE IND LTD 2004-09-30 JP disclosed
CN-1376660-A Synthesis of substituted trans-cinnamic aldehyde-natural yellow dyestuff from phenylpropyl alkyl derivatives COUNCIL SCIENT IND RES (IN) 2002-10-30 CN disclosed