Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | GNAO1 | P09471 | 8/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.37 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.37 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.37 |
| ▸ | GNAI3 | P08754 | 7/20 | 0.36 |
| ▸ | GNAI1 | P63096 | 7/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | GBA1 | P04062 | 1/20 | 0.31 |
| ▸ | ZDHHC9 | Q9Y397 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4944745 | 0.91 | TAAR1 (0.48) | TAAR1GNAO1S1PR1S1PR3S1PR5 | |
| SCHEMBL250854 | 0.89 | TAAR1 (0.53) | TAAR1GNAO1S1PR1S1PR3S1PR5 | |
| SCHEMBL4446755 | 0.89 | TAAR1 (0.53) | TAAR1GNAO1S1PR1S1PR3S1PR5 | |
| SCHEMBL6566400 | 0.87 | TAAR1 (0.52) | TAAR1GNAO1S1PR1S1PR3S1PR5 | |
| SCHEMBL27832364 | 0.87 | TAAR1 (0.52) | TAAR1GNAO1S1PR1S1PR3S1PR5 | |
| SCHEMBL6439309 | 0.87 | TAAR1 (0.52) | TAAR1GNAO1S1PR1S1PR3S1PR5 | |
| SCHEMBL11015512 | 0.87 | TAAR1 (0.52) | TAAR1GNAO1S1PR1S1PR3S1PR5 | |
| SCHEMBL28011845 | 0.87 | TAAR1 (0.52) | TAAR1GNAO1S1PR1S1PR3S1PR5 | |
| SCHEMBL7022097 | 0.87 | TAAR1 (0.52) | TAAR1GNAO1S1PR1S1PR3S1PR5 | |
| SCHEMBL28806944 | 0.87 | TAAR1 (0.39) | TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2004244376-A | METHOD FOR PRODUCING AMINOETHYLARYLPIPERAZINE DERIVATIVE | NISSAN CHEM IND LTD | 2004-09-02 | — | — | JP | disclosed |