Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 8/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.35 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | FYN | P06241 | 1/20 | 0.35 |
| ▸ | HCK | P08631 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | JAK3 | P52333 | 1/20 | 0.35 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.35 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.34 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.33 |
| ▸ | CDK2 | P24941 | 2/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | STAT3 | P40763 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1343126 | 0.86 | SMN1; SMN2 (0.34) | MAPK14MAPK13SMN1; SMN2ABCC1CCNE1 | |
| SCHEMBL1342828 | 0.85 | SMN1; SMN2 (0.43) | LCKMAPK14MAPK13EGFRFYN | |
| SCHEMBL1343766 | 0.84 | LCK (0.40) | LCKMAPK14MAPK13EGFRFYN | |
| SCHEMBL1344405 | 0.83 | LCK (0.39) | LCKMAPK14MAPK13EGFRFYN | |
| SCHEMBL1342321 | 0.83 | LCK (0.42) | LCKMAPK14MAPK13EGFRFYN | |
| SCHEMBL1342258 | 0.83 | LCK (0.45) | LCKMAPK14MAPK13EGFRFYN | |
| SCHEMBL1343084 | 0.83 | LCK (0.42) | LCKMAPK14MAPK13EGFRFYN | |
| SCHEMBL1341254 | 0.82 | SMN1; SMN2 (0.34) | JAK3SMN1; SMN2ABCC1CCNE1CDK2 | |
| SCHEMBL1340916 | 0.82 | SMN1; SMN2 (0.39) | MAPK14MAPK13SMN1; SMN2ABCC1GAA | |
| SCHEMBL6695568 | 0.82 | POLB (0.40) | LCKKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040122235-A1 | Aryl carbonyl derivatives as therapeutic agents | VTV THERAPEUTICS LLC | 2004-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040122235-A1 | Aryl carbonyl derivatives as therapeutic agents | GCK, GCKR, PDK2 | LCK 1793/4885MAPK14 1028/4885MAPK13 687/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.