Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.56 |
| ▸ | EP300 | Q09472 | 1/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.50 |
| ▸ | TERT | O14746 | 3/20 | 0.50 |
| ▸ | PPARG | P37231 | 3/20 | 0.50 |
| ▸ | PPARD | Q03181 | 3/20 | 0.50 |
| ▸ | PPARA | Q07869 | 3/20 | 0.50 |
| ▸ | BLM | P54132 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | FABP4 | P15090 | 2/20 | 0.50 |
| ▸ | GMNN | O75496 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL27523760 | 1.00 | TSHR (0.73) | TSHRALDH1A1MAPTABCC4EP300 | |
| Acetic Acid SCHEMBL2553321 | 1.00 | TSHR (0.73) | TSHRALDH1A1MAPTABCC4EP300 | |
| Acetic Acid SCHEMBL27695005 | 1.00 | TSHR (0.73) | TSHRALDH1A1MAPTABCC4EP300 | |
| Acetic Acid SCHEMBL27814165 | 1.00 | TSHR (0.73) | TSHRALDH1A1MAPTABCC4EP300 | |
| Acetic Acid SCHEMBL28114125 | 1.00 | TSHR (0.73) | TSHRALDH1A1MAPTABCC4EP300 | |
| Acetic Acid SCHEMBL27814163 | 1.00 | TSHR (0.73) | TSHRALDH1A1MAPTABCC4EP300 | |
| Acetic Acid SCHEMBL20420819 | 1.00 | TSHR (0.73) | TSHRALDH1A1MAPTABCC4EP300 | |
| Acetic Acid SCHEMBL30632143 | 1.00 | TSHR (0.73) | TSHRALDH1A1MAPTABCC4EP300 | |
| Acetic Acid SCHEMBL6511576 | 0.98 | TSHR (0.70) | TSHRALDH1A1MAPTABCC4EP300 | |
| Acetic Acid SCHEMBL28969508 | 0.98 | TSHR (0.70) | TSHRALDH1A1MAPTABCC4EP300 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111436187-B | Blend of a bio-stimulant based on folate impurity 10 and an agrochemical of interest | UPL有限责任公司 | 2022-12-13 | — | — | CN | disclosed |
| EP-1459626-B1 | Sustained release dispenser comprising two or more sex pheromone substances and a pest control method | SHINETSU CHEMICAL CO (JP) | 2020-01-29 | — | — | EP | disclosed |
| CN-102599156-B | Sex attractant and trapping core for Dendrolimus tabulaeformis and preparation method of trapping core | INST FOREST ECOLOGY ENVIRONMENT & PROT CAF | 2014-11-12 | — | — | CN | disclosed |
| CN-102599156-A | Sex attractant and trapping core for Dendrolimus tabulaeformis and preparation method of trapping core | INST FOREST ECOLOGY ENVIRONMENT & PROT CAF | 2012-07-25 | — | — | CN | disclosed |
| EP-1459626-A1 | Sustained release dispenser comprising two or more sex pheromone substances and a pest control method | Shin-Etsu Chemical Co., Ltd. (JP) | 2004-09-22 | — | — | EP | disclosed |