Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 5/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.66 |
| ▸ | MEN1 | O00255 | 2/20 | 0.66 |
| ▸ | STAT3 | P40763 | 1/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.66 |
| ▸ | ENPP1 | P22413 | 3/20 | 0.65 |
| ▸ | EGFR | P00533 | 5/20 | 0.64 |
| ▸ | BRD4 | O60885 | 1/20 | 0.64 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.64 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.61 |
| ▸ | HTT | P42858 | 3/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | LCK | P06239 | 1/20 | 0.60 |
| ▸ | FLT1 | P17948 | 1/20 | 0.56 |
| ▸ | KDR | P35968 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30080122 | 0.92 | ENPP1 (0.70) | MAPK1KMT2AMEN1STAT3SMN1; SMN2 | |
| SCHEMBL23751419 | 0.92 | ENPP1 (0.70) | MAPK1KMT2AMEN1STAT3SMN1; SMN2 | |
| SCHEMBL23762372 | 0.90 | ENPP1 (0.72) | MAPK1KMT2AMEN1STAT3SMN1; SMN2 | |
| SCHEMBL23762274 | 0.89 | ENPP1 (0.72) | MAPK1KMT2AMEN1STAT3SMN1; SMN2 | |
| SCHEMBL23762332 | 0.88 | ENPP1 (0.73) | MAPK1KMT2AMEN1STAT3SMN1; SMN2 | |
| SCHEMBL8351408 | 0.87 | MAPK1 (0.67) | MAPK1KMT2AMEN1STAT3SMN1; SMN2 | |
| SCHEMBL18292695 | 0.85 | MAPK1 (0.66) | MAPK1KMT2AMEN1STAT3SMN1; SMN2 | |
| SCHEMBL8345731 | 0.83 | EGFR (0.66) | MAPK1KMT2AMEN1STAT3SMN1; SMN2 | |
| SCHEMBL11857812 | 0.83 | ENPP1 (0.73) | MAPK1KMT2AMEN1STAT3SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL5911719 | 0.82 | ENPP1 (0.61) | MAPK1KMT2AMEN1STAT3SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040180925-A1 | Dipeptidylpeptidase-IV inhibitor | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2004-09-16 | — | — | US | disclosed |
| EP-1354882-A1 | DIPEPTIDYL PEPTIDASE IV INHIBITOR | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2003-10-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040180925-A1 | Dipeptidylpeptidase-IV inhibitor | DPP4, DPP3, DPP9 | MAPK1 3092/4885KMT2A 4164/4885MEN1 3315/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.