SCHEMBL6701412

SCHEMBL6701412

CC1CCC(C(C)C)C(OC(=O)/C=C\C(=O)OC2CC(C)CCC2C(C)C)C1

nearest known ligand 0.60

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 3/20 0.57
ALDH1A1 P00352 9/20 0.52
HPGD P15428 2/20 0.52
CYP19A1 P11511 2/20 0.51
TRPA1 O75762 2/20 0.46
TRPM8 Q7Z2W7 2/20 0.46
TSHR P16473 2/20 0.44
MAPT P10636 2/20 0.44
LMNA P02545 2/20 0.44
USP2 O75604 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
KDM4E B2RXH2 1/20 0.43
GAA P10253 1/20 0.43
MAPK1 P28482 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13674748 1.00 EPHX1 (0.57) EPHX1ALDH1A1HPGDCYP19A1TRPA1
SCHEMBL545429 1.00 EPHX1 (0.57) EPHX1ALDH1A1HPGDCYP19A1TRPA1
SCHEMBL13476390 1.00 EPHX1 (0.57) EPHX1ALDH1A1HPGDCYP19A1TRPA1
SCHEMBL13675571 1.00 EPHX1 (0.57) EPHX1ALDH1A1HPGDCYP19A1TRPA1
SCHEMBL13674746 1.00 EPHX1 (0.57) EPHX1ALDH1A1HPGDCYP19A1TRPA1
SCHEMBL6737565 1.00 EPHX1 (0.57) EPHX1ALDH1A1HPGDCYP19A1TRPA1
SCHEMBL13476726 1.00 EPHX1 (0.57) EPHX1ALDH1A1HPGDCYP19A1TRPA1
SCHEMBL16387737 1.00 EPHX1 (0.57) EPHX1ALDH1A1HPGDCYP19A1TRPA1
SCHEMBL14226245 1.00 EPHX1 (0.57) EPHX1ALDH1A1HPGDCYP19A1TRPA1
SCHEMBL15335366 1.00 EPHX1 (0.57) EPHX1ALDH1A1HPGDCYP19A1TRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115707451-A Clonazepam oral solution 北京万全德众医药生物技术有限公司 2023-02-21 CN claimed
CN-111603415-B Oral care compositions comprising hops extract and uses thereof 好维股份有限公司 2023-12-19 CN disclosed
CN-117089948-A Cooling factor modified nylon fiber with special-shaped cross section, preparation method and application thereof in cool sense anti-ultraviolet fabric 汕头市兴裕泰纺织有限公司 2023-11-21 CN disclosed
CN-115707451-A Clonazepam oral solution 北京万全德众医药生物技术有限公司 2023-02-21 CN disclosed
CN-108610257-B Menthol derivatives, mixtures thereof, and methods for preparing and using menthol derivatives 上海大学 2021-12-03 CN disclosed
CN-108610257-A The preparation method and application of menthol derivative, its mixture and menthol derivative 上海大学 2018-10-02 CN disclosed
CN-103168899-A Menthyl ester containing cooling compositions KRAFT FOODS GLOBAL BRANDS LLC 2013-06-26 CN disclosed
CN-101282707-B Cooling compositions comprising menthyl esters KRAFT FOODS GLOBAL BRANDS LLC 2013-03-27 CN disclosed
WO-2011162562-A2 [6+5] FUSED BICYCLES AS A THROMBIN ANTAGONIST, PROCESS FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE BICYCLES KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2011-12-29 WO disclosed
CN-101282707-A Cooling compositions comprising menthyl esters CADBURY ADAMS USA LLC (US) 2008-10-08 CN disclosed
US-20040254395-A1 Ozonolysis process for preparing menthyl glyoxylate hydrate COOK PHILLIP MICHAEL (US) 2004-12-16 US disclosed