Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 6/20 | 0.46 |
| ▸ | FOXM1 | Q08050 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 3/20 | 0.43 |
| ▸ | MAOB | P27338 | 3/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.43 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6701684 | 1.00 | KDM1A (0.46) | KDM1AFOXM1MAOAMAOBOPRM1 | |
| SCHEMBL6701685 | 1.00 | KDM1A (0.46) | KDM1AFOXM1MAOAMAOBOPRM1 | |
| SCHEMBL6699442 | 0.87 | P4HTM (0.43) | KDM1AFOXM1MAOAMAOBKMT2A | |
| SCHEMBL6280183 | 0.87 | P4HTM (0.43) | KDM1AFOXM1MAOAMAOBKMT2A | |
| SCHEMBL6699445 | 0.87 | P4HTM (0.43) | KDM1AFOXM1MAOAMAOBKMT2A | |
| SCHEMBL6256635 | 0.77 | P4HTM (0.50) | MAOAMAOBP4HTM | |
| SCHEMBL6253433 | 0.77 | EPHX2 (0.44) | KDM1AMAOAMAOB | |
| SCHEMBL6253438 | 0.77 | EPHX2 (0.44) | KDM1AMAOAMAOB | |
| SCHEMBL6253429 | 0.77 | EPHX2 (0.44) | KDM1AMAOAMAOB | |
| SCHEMBL6268294 | 0.76 | KDM1A (0.46) | KDM1AFOXM1MAOAMAOBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040152715-A1 | Cycloalkylene amide compounds as NR2B receptor antagonists | KAWAI MAKOTO (JP) | 2004-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040152715-A1 | Cycloalkylene amide compounds as NR2B receptor antagonists | GRIN1, GRIN3A, GRIN2A | KDM1A 855/4885FOXM1 2508/4885MAOA 2028/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.