Trientine

Trientine

SCHEMBL670240

N.NCCNCCNCCN

nearest known ligand 0.92

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 5/20 0.92
CA6 P23280 5/20 0.92
CA7 P43166 5/20 0.92
CA9 Q16790 5/20 0.92
CA14 Q9ULX7 5/20 0.92
CA5B Q9Y2D0 5/20 0.92
CA2 P00918 4/20 0.92
CA4 P22748 4/20 0.92
CA5A P35218 4/20 0.92
LMNA P02545 3/20 0.92
TDP1 Q9NUW8 3/20 0.92
CA3 P07451 3/20 0.92
ALOX15 P16050 3/20 0.92
CA1 P00915 2/20 0.92
ALDH1A1 P00352 1/20 0.92
TP53 P04637 1/20 0.92
KDM4E B2RXH2 1/20 0.85
MEN1 O00255 2/20 0.83
RECQL P46063 2/20 0.83
KMT2A Q03164 2/20 0.83

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trientine SCHEMBL7557252 1.00 CA12 (0.92) CA12CA6CA7CA9CA14
Ammonia Solution, Strong SCHEMBL902204 0.96
Ammonia Solution, Strong SCHEMBL7559317 0.96
Trientine SCHEMBL3840289 0.96 CA12 (1.00) CA12CA6CA7CA9CA14
SCHEMBL2538760 0.96 CA12 (1.00) CA12CA6CA7CA9CA14
SCHEMBL25342018 0.96 CA12 (1.00) CA12CA6CA7CA9CA14
SCHEMBL181401 0.96 CA12 (1.00) CA12CA6CA7CA9CA14
SCHEMBL25340653 0.96 CA12 (1.00) CA12CA6CA7CA9CA14
Trientine SCHEMBL15439 0.96 CA12 (1.00) CA12CA6CA7CA9CA14
SCHEMBL25342922 0.96 CA12 (1.00) CA12CA6CA7CA9CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019227559-A1 SOLID CONDUCTIVE GEL SUITABLE FOR ELECTROCHEMICAL SYSTEM AND PREPARATION METHOD THEREFOR 江苏大学 (CN) 2019-12-05 WO claimed
CN-103113959-A High-hydrolysis stability organic ammonium borate extreme-pressure antiwear additive and preparation method thereof UNIV SHANGHAI JIAOTONG 2013-05-22 CN claimed
CN-110582526-B Epoxy resin composition containing sulfanilamide 陶氏环球技术有限责任公司 2023-04-04 CN disclosed
CN-111500236-A Ballastless track surface crack repairing material and preparation method thereof 武汉比邻科技发展有限公司 2020-08-07 CN disclosed
US-20200148811-A1 SULFANILAMIDE CONTAINING EPOXY RESIN COMPOSITIONS DOW GLOBAL TECHNOLOGIES LLC (US) 2020-05-14 US disclosed
EP-3635025-A1 SULFANILAMIDE CONTAINING EPOXY RESIN COMPOSITIONS Dow Global Technologies LLC (US) 2020-04-15 EP disclosed
CN-110582526-A epoxy resin composition containing sulfanilamide 陶氏环球技术有限责任公司 2019-12-17 CN disclosed
WO-2019227559-A1 SOLID CONDUCTIVE GEL SUITABLE FOR ELECTROCHEMICAL SYSTEM AND PREPARATION METHOD THEREFOR 江苏大学 (CN) 2019-12-05 WO disclosed
EP-3475396-A1 GAS HYDRATE INHIBITORS Lubrizol Oilfield Solutions, Inc. (US) 2019-05-01 EP disclosed
WO-2018208420-A1 SULFANILAMIDE CONTAINING EPOXY RESIN COMPOSITIONS DOW GLOBAL TECHNOLOGIES LLC (US) 2018-11-15 WO disclosed
WO-2017223306-A1 GAS HYDRATE INHIBITORS Lubrizol Oilfield Solutions, Inc. (US) 2017-12-28 WO disclosed
CN-103113959-A High-hydrolysis stability organic ammonium borate extreme-pressure antiwear additive and preparation method thereof UNIV SHANGHAI JIAOTONG 2013-05-22 CN disclosed
WO-2012024524-A1 EARLY APPLICATIONS OF ENCAPSULATED ACETAMIDES FOR REDUCED INJURY IN CROPS MONSANTO TECHNOLOGY LLC (US) 2012-02-23 WO disclosed
US-20110159222-A1 FLUOROCARBON THERMOPLASTIC MATERIALS CURED WITH ORGANIC PRIMARY AMINES CITICORP NORTH AMERICA, INC., AS AGENT 2011-06-30 US disclosed
US-20100104864-A1 THERMALLY CROSSLINKING POLYACRYLATES AND METHOD FOR PRODUCING THE SAME TESA SE (DE) 2010-04-29 US disclosed
US-5143999-A For sealing, adhesives, molding resins, casting resins or coating compositions CIBA-GEIGY CORPORATION (US) 1992-09-01 US disclosed
WO-1992010285-A1 MICROCAPSULE HAVING TEMPERATURE-DEPENDENT PERMEABILITY PROFILE LANDEC LABS, INC. (US) 1992-06-25 WO disclosed
CN-1056681-A Selectivity prepares straight chain Triethylenetetramine (TETA) and N-aminoethyl ethanolamine UNION CARBIDE CHEM PLASTIC (US) 1991-12-04 CN disclosed
EP-0255721-A2 Silver halide emulsions and photographic materials FUJI PHOTO FILM CO., LTD. (JP) 1988-02-10 EP disclosed
US-4175069-A Plasticization of neutralized sulfonated elastomeric polymer EXXON RESEARCH & ENGINEERING CO. (US) 1979-11-20 US disclosed