Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6704365 | 0.99 | PDGFRB (1.00) | PDGFRB | |
| SCHEMBL6704571 | 0.99 | PDGFRB (1.00) | PDGFRB | |
| SCHEMBL906341 | 0.94 | PDGFRB (1.00) | PDGFRB | |
| SCHEMBL6705510 | 0.93 | PDGFRB (1.00) | PDGFRB | |
| SCHEMBL906239 | 0.91 | PDGFRB (1.00) | PDGFRB | |
| SCHEMBL6703372 | 0.87 | PDGFRB (0.80) | PDGFRB | |
| SCHEMBL6704362 | 0.86 | PDGFRB (0.79) | PDGFRB | |
| SCHEMBL6704570 | 0.86 | PDGFRB (0.79) | PDGFRB | |
| SCHEMBL5907679 | 0.86 | PDGFRB (0.79) | PDGFRB | |
| SCHEMBL5033009 | 0.85 | PDGFRB (0.93) | PDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040259881-A1 | Nitrogenous heterocyclic compounds | KYOWA HAKKO KOGYO CO, LTD. (JP) | 2004-12-23 | — | — | US | claimed |
| EP-1309567-A2 | NITROGENOUS HETEROCYCLIC COMPOUNDS | Millennium Pharmaceuticals, Inc. (US) | 2003-05-14 | — | — | EP | claimed |
| WO-2002016360-A2 | NITROGENOUS HETEROCYCLIC COMPOUNDS | COR THERAPEUTICS, INC. (US) | 2002-02-28 | — | — | WO | claimed |
| US-20040259881-A1 | Nitrogenous heterocyclic compounds | KYOWA HAKKO KOGYO CO, LTD. (JP) | 2004-12-23 | — | — | US | disclosed |
| EP-1309567-A2 | NITROGENOUS HETEROCYCLIC COMPOUNDS | Millennium Pharmaceuticals, Inc. (US) | 2003-05-14 | — | — | EP | disclosed |
| WO-2002016360-A2 | NITROGENOUS HETEROCYCLIC COMPOUNDS | COR THERAPEUTICS, INC. (US) | 2002-02-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040259881-A1 | Nitrogenous heterocyclic compounds | WNK2, CDK5, PDGFRA | PDGFRB 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.