Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 12/20 | 0.55 |
| ▸ | PREP | P48147 | 7/20 | 0.47 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.46 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | FAP | Q12884 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5077374 | 0.85 | DPP4 (0.75) | DPP4PREPDPP7DPP8 | |
| SCHEMBL6703266 | 0.82 | DPP4 (0.56) | DPP4PREPDPP7DPP8CYP2D6 | |
| SCHEMBL6703269 | 0.82 | DPP4 (0.56) | DPP4PREPDPP7DPP8CYP2D6 | |
| SCHEMBL6700347 | 0.81 | DPP4 (0.52) | DPP4PREPDPP7DPP8CYP2D6 | |
| SCHEMBL6700341 | 0.81 | DPP4 (0.52) | DPP4PREPDPP7DPP8CYP2D6 | |
| SCHEMBL5141299 | 0.79 | DPP4 (0.59) | DPP4DPP7DPP8DPP9FAP | |
| SCHEMBL5141298 | 0.79 | DPP4 (0.59) | DPP4DPP7DPP8DPP9FAP | |
| Oxalic Acid SCHEMBL6696017 | 0.79 | DPP4 (0.66) | DPP4PREPDPP7DPP8 | |
| SCHEMBL6702155 | 0.73 | DPP4 (0.75) | DPP4PREPDPP7DPP8 | |
| SCHEMBL6595949 | 0.71 | DPP4 (1.00) | DPP4DPP7DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040180925-A1 | Dipeptidylpeptidase-IV inhibitor | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2004-09-16 | — | — | US | disclosed |
| EP-1354882-A1 | DIPEPTIDYL PEPTIDASE IV INHIBITOR | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2003-10-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040180925-A1 | Dipeptidylpeptidase-IV inhibitor | DPP4, DPP3, DPP9 | DPP4 1/4885PREP 19/4885DPP7 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.