⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28445 | 0.78 | — | — | |
| SCHEMBL452881 | 0.78 | — | — | |
| SCHEMBL110738 | 0.72 | — | — | |
| SCHEMBL110739 | 0.72 | — | — | |
| SCHEMBL5620011 | 0.69 | — | — | |
| SCHEMBL14378420 | 0.69 | — | — | |
| SCHEMBL11235492 | 0.69 | — | — | |
| SCHEMBL8152783 | 0.69 | — | — | |
| SCHEMBL1830629 | 0.67 | — | — | |
| SCHEMBL6266535 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040099975-A1 | Method of preparing a surface modifier for nanoparticles, surface-modified inorganic oxide nanoparticles, and applications thereof | FAR EASTERN TEXTILE LTD. | 2004-05-27 | — | — | US | claimed |
| CN-1508198-A | Preparation method of nano-scale particle surface modifier, nano inorganic oxide dispersion and application thereof | 远东纺织股份有限公司 | 2004-06-30 | — | — | CN | disclosed |
| US-20040099975-A1 | Method of preparing a surface modifier for nanoparticles, surface-modified inorganic oxide nanoparticles, and applications thereof | FAR EASTERN TEXTILE LTD. | 2004-05-27 | — | — | US | disclosed |
| EP-0842934-B1 | 5-HT1F agonists | LILLY CO ELI (US) | 2003-10-29 | — | — | EP | disclosed |
| EP-1082958-A2 | 5-HT1F agonists in chronic pain | ELI LILLY AND COMPANY (US) | 2001-03-14 | — | — | EP | disclosed |
| US-5919936-A | 5-HT1F AGONIST INTERMEDIATES | ELI LILLY AND COMPANY (US) | 1999-07-06 | — | — | US | disclosed |
| US-5817671-A | ANTISEROTONIN AGENT; ANALGESICS; MIGRAINE THERAPY; COMPOUND CONTAINING PYRROLO(3,2-B)PYRIDINE RING | ELI LILLY AND COMPANY (US) | 1998-10-06 | — | — | US | disclosed |
| WO-1998020875-A1 | 5-HT1F AGONISTS | ELI LILLY AND COMPANY (US) | 1998-05-22 | — | — | WO | disclosed |
| EP-0842934-A1 | 5-HT1F agonists | ELI LILLY AND COMPANY (US) | 1998-05-20 | — | — | EP | disclosed |