Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28297798 | 0.94 | CYP1A2 (0.43) | CYP1A2CYP2D6MAPTKMT2AKCNN4 | |
| SCHEMBL8588532 | 0.90 | MAPT (0.48) | CYP1A2CYP2D6MAPTKMT2AKCNN4 | |
| SCHEMBL226184 | 0.85 | CYP1A2 (0.56) | CYP1A2CYP2D6MAPTKMT2AKCNN4 | |
| SCHEMBL21269074 | 0.82 | CYP1A2 (0.54) | CYP1A2CYP2D6MAPTKMT2AKCNN4 | |
| SCHEMBL21269337 | 0.82 | CYP1A2 (0.54) | CYP1A2CYP2D6MAPTKMT2AKCNN4 | |
| SCHEMBL21269593 | 0.82 | CYP1A2 (0.54) | CYP1A2CYP2D6MAPTKMT2AKCNN4 | |
| SCHEMBL3233296 | 0.76 | CYP1A2 (0.48) | CYP1A2CYP2D6MAPTKMT2AKCNN4 | |
| Nitrous Acid SCHEMBL7049171 | 0.76 | CYP1A2 (0.48) | CYP1A2CYP2D6MAPTKMT2AKCNN4 | |
| SCHEMBL1667198 | 0.75 | MAPT (0.48) | CYP1A2CYP2D6MAPTKMT2AKCNN4 | |
| SCHEMBL3523419 | 0.75 | KCNN4 (0.58) | CYP1A2CYP2D6MAPTKMT2AKCNN4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3060574-A1 | ALPHA BETA MODULATING PEPTIDES | Alzhyme Pty Ltd (AU) | 2016-08-31 | — | — | EP | disclosed |
| WO-2015058258-A1 | AΒ MODULATING PEPTIDES | ALZHYME PTY LTD (AU) | 2015-04-30 | — | — | WO | disclosed |
| US-20040234739-A1 | Water-soluble hotmelt adhesive | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) | 2004-11-25 | — | — | US | disclosed |
| EP-1263454-A2 | METHODS FOR ENHANCING THE BIOAVAILABILITY OF A DRUG | Praecis Pharmaceuticals Incorporated (US) | 2002-12-11 | — | — | EP | disclosed |
| WO-2000052048-A9 | MODULATORS OF BETA-AMYLOID PEPTIDE AGGREGATION COMPRISING D-AMINO ACIDS | PRAECIS PHARM INC (US) | 2002-04-11 | — | — | WO | disclosed |
| EP-1189882-A1 | BIPHENYL BUTYRIC ACID DERIVATIVE AS A MATRIX METALLOPROTEINASE INHIBITOR | SAMSUNG ELECTRONICS Co. Ltd. (KR) | 2002-03-27 | — | — | EP | disclosed |
| WO-2001083445-A1 | BIPHENYL BUTYRIC ACID DERIVATIVE AS A MATRIX METALLOPROTEINASE INHIBITOR | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2001-11-08 | — | — | WO | disclosed |
| WO-2001058470-A2 | METHODS FOR ENHANCING THE BIOAVAILABILITY OF A DRUG | PRAECIS PHARMACEUTICALS INCORPORATED (US) | 2001-08-16 | — | — | WO | disclosed |