SCHEMBL670677

SCHEMBL670677

Cc1ccc(C(=O)c2c(C)n(CCN3CCOCC3)c3ccc(Cl)cc23)c2ccccc12

nearest known ligand 0.81

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 1/20 0.63
CNR2 P34972 1/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10093009 0.93 CNR1 (0.62) CNR1CNR2
SCHEMBL15142718 0.90 CNR2 (0.66) CNR1CNR2
SCHEMBL10093007 0.90 CNR2 (0.77) CNR1CNR2
SCHEMBL10093008 0.90 CNR2 (0.64) CNR1CNR2
SCHEMBL670365 0.87 CNR1 (0.68) CNR1CNR2
SCHEMBL670149 0.86 CNR1 (0.57) CNR1CNR2
SCHEMBL15142732 0.85 CNR1 (0.64) CNR1CNR2
SCHEMBL10093006 0.85 CNR1 (0.63) CNR1CNR2
SCHEMBL15142731 0.84 CNR1 (0.57) CNR1CNR2
SCHEMBL10093012 0.82 CNR1 (0.67) CNR1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9034895-B2 Composition and methods for treating glioblastoma UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (US) 2015-05-19 US disclosed
US-9034895-B2 Composition and methods for treating glioblastoma UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (US) 2015-05-19 US disclosed
US-9034895-B2 Composition and methods for treating glioblastoma UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (US) 2015-05-19 US disclosed
EP-2606032-B1 COMPOSITION AND METHODS FOR TREATING GLIOBLASTOMAS UNIV WASHINGTON CT COMMERCIALI (US) 2015-01-07 EP disclosed
US-20130197026-A1 COMPOSITION AND METHODS FOR TREATING GLIOBLASTOMA Unversity of Washington Through its Center for Commercialization (US) 2013-08-01 US disclosed
US-20130197026-A1 COMPOSITION AND METHODS FOR TREATING GLIOBLASTOMA Unversity of Washington Through its Center for Commercialization (US) 2013-08-01 US disclosed
US-20130197026-A1 COMPOSITION AND METHODS FOR TREATING GLIOBLASTOMA Unversity of Washington Through its Center for Commercialization (US) 2013-08-01 US disclosed
EP-2606032-A2 COMPOSITION AND METHODS FOR TREATING GLIOBLASTOMA University Of Washington Through Its Center For Commercialization (US) 2013-06-26 EP disclosed
WO-2012024670-A2 COMPOSITION AND METHODS FOR TREATING GLIOBLASTOMA UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (US) 2012-02-23 WO disclosed
WO-2012024670-A2 COMPOSITION AND METHODS FOR TREATING GLIOBLASTOMA UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (US) 2012-02-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130197026-A1 COMPOSITION AND METHODS FOR TREATING GLIOBLASTOMA MGMT, NEFM, TP53 CNR1 2351/4885CNR2 1823/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.