SCHEMBL6706898

SCHEMBL6706898

Cc1ccc(/C(C#N)=N\O)cc1C

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRSS1 P07477 1/20 0.42
PRSS2 P07478 1/20 0.42
PRSS3 P35030 1/20 0.42
HSD17B10 Q99714 2/20 0.42
LMNA P02545 4/20 0.40
KMT2A Q03164 3/20 0.40
GFER P55789 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
TP53 P04637 2/20 0.40
HTT P42858 4/20 0.39
SMN1; SMN2 Q16637 3/20 0.39
CES2 O00748 1/20 0.39
CES1 P23141 1/20 0.39
MAPT P10636 6/20 0.37
POLB P06746 2/20 0.37
NFKB1 P19838 1/20 0.37
NFKB2 Q00653 1/20 0.37
RELA Q04206 1/20 0.37
ALDH1A1 P00352 8/20 0.36
KDM4E B2RXH2 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6706899 1.00 PRSS1 (0.42) PRSS1PRSS2PRSS3HSD17B10LMNA
SCHEMBL6706099 0.78 HSD17B10 (0.46) HSD17B10LMNAKMT2ATP53HTT
SCHEMBL10753245 0.78 HSD17B10 (0.46) HSD17B10LMNAKMT2ATP53HTT
SCHEMBL6706101 0.78 HSD17B10 (0.46) HSD17B10LMNAKMT2ATP53HTT
SCHEMBL17966195 0.76 HSD17B10 (0.45) HSD17B10KMT2ATP53SMN1; SMN2POLB
SCHEMBL17966196 0.76 HSD17B10 (0.45) HSD17B10KMT2ATP53SMN1; SMN2POLB
SCHEMBL2259817 0.75 MAPT (0.37) PRSS1PRSS2PRSS3LMNAKMT2A
SCHEMBL2259819 0.75 MAPT (0.37) PRSS1PRSS2PRSS3LMNAKMT2A
SCHEMBL7786971 0.73 HSD17B10 (0.36) HSD17B10LMNAKMT2AL3MBTL1TP53
SCHEMBL7781768 0.73 PDE4A (0.54) KMT2ASMN1; SMN2MAPTPOLBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6770420-B2 Alkylsulfonyloximes for high-resolution i-line photoresists of high sensitivity CIBA SPECIALTY CHEMICALS CORPORATION 2004-08-03 US disclosed
US-20040013974-A1 Alkylsulfonyloximes for high-resolution i-line photoresists of high sensitivity DIETLIKER KURT (CH) 2004-01-22 US disclosed
EP-0925529-B1 ALKYSULFONYLOXIMES FOR HIGH-RESOLUTION I-LINE PHOTORESISTS OF HIGH SENSITIVITY CIBA SC HOLDING AG (CH) 2003-04-16 EP disclosed
EP-0925529-A1 ALKYSULFONYLOXIMES FOR HIGH-RESOLUTION I-LINE PHOTORESISTS OF HIGH SENSITIVITY Ciba SC Holding AG (CH) 1999-06-30 EP disclosed
WO-1998010335-A1 ALKYSULFONYLOXIMES FOR HIGH-RESOLUTION I-LINE PHOTORESISTS OF HIGH SENSITIVITY CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 1998-03-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040013974-A1 Alkylsulfonyloximes for high-resolution i-line photoresists of high sensitivity SULT1E1, CCNT1, CCNE1 PRSS1 968/4885PRSS2 783/4885PRSS3 987/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.