Ethylene Glycol

Ethylene Glycol

SCHEMBL6706940

C=CCOC(=O)C(=C)C.OCCO

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.45
THRB P10828 1/20 0.42
ALDH1A1 P00352 6/20 0.40
CYP3A4 P08684 1/20 0.37
TDP1 Q9NUW8 2/20 0.36
MAPT P10636 5/20 0.35
CACNA1B Q00975 1/20 0.35
APBA1 Q02410 1/20 0.35
HSD17B10 Q99714 2/20 0.33
KDM4E B2RXH2 2/20 0.33
TP53 P04637 1/20 0.33
HPGD P15428 1/20 0.33
POLB P06746 2/20 0.32
APEX1 P27695 1/20 0.32
HTT P42858 1/20 0.32
MEN1 O00255 3/20 0.31
KMT2A Q03164 3/20 0.31
MAPK1 P28482 2/20 0.31
LMNA P02545 1/20 0.31
GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL28243084 0.94 TSHR (0.41) TSHRTHRBALDH1A1CYP3A4TDP1
SCHEMBL1057516 0.94 TSHR (0.50) TSHRTHRBALDH1A1CYP3A4TDP1
SCHEMBL28226548 0.94 TSHR (0.50) TSHRTHRBALDH1A1CYP3A4TDP1
SCHEMBL8921614 0.94
SCHEMBL22017 0.94
SCHEMBL6269152 0.94
SCHEMBL4823985 0.94
1,4-Butanediol SCHEMBL6757330 0.92 TSHR (0.43) TSHRTHRBALDH1A1CYP3A4TDP1
Ethylene SCHEMBL460398 0.91 TSHR (0.48) TSHRTHRBALDH1A1CYP3A4TDP1
Acetone SCHEMBL11804126 0.91 TSHR (0.48) TSHRTHRBALDH1A1CYP3A4TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004113406-A1 PROCESS FOR MAKING GRAFT COPOLYMERS IN MOLTEN STATE USING A REACTIVE, PEROXIDE-CONTAINING OLEFIN POLYMER BASELL POLIOLEFINE ITALIA S.R.L. (US) 2004-12-29 WO claimed
EP-0334051-B1 Electron beam-curable composition for release material and process for preparation of release material SHOWA DENKO KK (JP) 1996-05-01 EP claimed
US-5350550-A Method of production of a plastic laminate NIPPON ZEON CO., LTD. (JP) 1994-09-27 US claimed
US-5206092-A Irradiating a composition of polyolefin resin, dimethylsiloxane and a polyfunctional compound having unsaturation or thiol groups SHOWA DENKO K.K. (JP) 1993-04-27 US claimed
EP-3040354-B1 BLOCK COPOLYMER LG CHEMICAL LTD (KR) 2020-11-04 EP disclosed
US-10308751-B2 Block copolymer LG CHEM, LTD. (KR) 2019-06-04 US disclosed
CN-104962242-B A kind of low degree of supercooling phase-change material micro-capsule and preparation method thereof 天津工业大学 2017-12-01 CN disclosed
CN-104619735-B Ultra-violet solidified urethane acrylate composition, film shaped body, blooming and the manufacture method of film shaped body DIC株式会社 2016-08-17 CN disclosed
US-20160208039-A1 BLOCK COPOLYMER LG CHEM, LTD. (KR) 2016-07-21 US disclosed
EP-3040354-A1 BLOCK COPOLYMER LG Chem, Ltd. (KR) 2016-07-06 EP disclosed
EP-0334051-B1 Electron beam-curable composition for release material and process for preparation of release material SHOWA DENKO KK (JP) 1996-05-01 EP disclosed
US-5206092-A Irradiating a composition of polyolefin resin, dimethylsiloxane and a polyfunctional compound having unsaturation or thiol groups SHOWA DENKO K.K. (JP) 1993-04-27 US disclosed
EP-0334051-A2 Electron beam-curable composition for release material and process for preparation of release material SHOWA DENKO KABUSHIKI KAISHA (JP) 1989-09-27 EP disclosed