Methyl 2-Methylbutanoate

Methyl 2-Methylbutanoate

SCHEMBL6708352

CCC(C)C(=O)OC.CCCCC(=O)OC.CCCCC(=O)OCC.CCOC(=O)C(C)CC

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.42
TSHR P16473 3/20 0.41
MAPT P10636 1/20 0.41
KMT2A Q03164 2/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
POLB P06746 1/20 0.40
CYP3A4 P08684 1/20 0.40
ATM Q13315 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.39
DGKA P23743 1/20 0.39
KDM5A P29375 2/20 0.38
MGAM O43451 1/20 0.37
GAA P10253 1/20 0.37
SI P14410 1/20 0.37
MGAM2 Q2M2H8 1/20 0.37
LMNA P02545 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3911368 0.91 CYP1A2 (0.50) CYP1A2TSHRMAPTKMT2APOLB
Methyl 2-Methylbutanoate SCHEMBL3915351 0.91 TSHR (0.50) TSHRMAPTCA1CA2POLB
SCHEMBL26598404 0.85 MAPT (0.54) CYP1A2TSHRMAPTKMT2ACYP3A4
SCHEMBL22498473 0.84 MAPT (0.57) CYP1A2TSHRMAPTKMT2ACYP3A4
SCHEMBL30317638 0.84 MAPT (0.57) CYP1A2TSHRMAPTKMT2ACYP3A4
SCHEMBL1869381 0.84 TSHR (0.43) TSHRKMT2ACA1CA2POLB
SCHEMBL1865676 0.83 TSHR (0.45) CYP1A2TSHRMAPTKMT2ACA1
SCHEMBL7636079 0.80 TSHR (0.54) CYP1A2TSHRMAPTCA2DGKA
SCHEMBL27430679 0.80 TSHR (0.54) CYP1A2TSHRMAPTCA2DGKA
SCHEMBL11892835 0.78 TSHR (0.52) CYP1A2TSHRMAPTKMT2ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040238785-A1 Ester-containing fluid compositions VAN DRIESSCHE EDDY (BE) 2004-12-02 US disclosed
EP-1259471-A1 ESTER-CONTAINING FLUID COMPOSITIONS Exxonmobil Chemical Patents Inc. (US) 2002-11-27 EP disclosed
US-20020005503-A1 Ester-containing fluid compositions EXXONMOBIL CHEMICAL PATENTS INC. 2002-01-17 US disclosed
WO-2001047858-A1 ESTER-CONTAINING FLUID COMPOSITIONS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2001-07-05 WO disclosed