Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 18/20 | 0.75 |
| ▸ | FGFR1 | P11362 | 7/20 | 0.75 |
| ▸ | LCK | P06239 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5247427 | 0.86 | KDR (1.00) | KDRFGFR1LCK | |
| SCHEMBL5247433 | 0.86 | KDR (1.00) | KDRFGFR1LCK | |
| SCHEMBL5249168 | 0.82 | KDR (1.00) | KDRFGFR1LCK | |
| SCHEMBL5786700 | 0.82 | KDR (1.00) | KDRFGFR1LCK | |
| SCHEMBL5786696 | 0.82 | KDR (1.00) | KDRFGFR1LCK | |
| SCHEMBL5250666 | 0.82 | KDR (1.00) | KDRFGFR1LCK | |
| SCHEMBL5255416 | 0.82 | KDR (1.00) | KDRFGFR1LCK | |
| SCHEMBL5252137 | 0.81 | KDR (1.00) | KDRFGFR1LCK | |
| SCHEMBL6710523 | 0.81 | KDR (0.51) | KDRFGFR1 | |
| SCHEMBL5253288 | 0.80 | KDR (0.79) | KDRFGFR1LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040171634-A1 | Indazole compounds and pharmaceutical compositions for inhibiting protein kinases, and methods for their use | AGOURON PHARMACEUTICALS, LLC | 2004-09-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040171634-A1 | Indazole compounds and pharmaceutical compositions for inhibiting protein kinases, and methods for their use | CDK3, BRAF, ROCK1 | KDR 60/4885FGFR1 262/4885LCK 39/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.