Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 13/20 | 0.51 |
| ▸ | NPY1R | P25929 | 8/20 | 0.51 |
| ▸ | NPY2R | P49146 | 6/20 | 0.51 |
| ▸ | NPY5R | Q15761 | 5/20 | 0.51 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.46 |
| ▸ | APLNR | P35414 | 1/20 | 0.42 |
| ▸ | GLP1R | P43220 | 1/20 | 0.42 |
| ▸ | SCTR | P47872 | 1/20 | 0.42 |
| ▸ | VIPR2 | P41587 | 2/20 | 0.41 |
| ▸ | VIPR1 | P32241 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6710584 | 1.00 | NPY4R (0.51) | NPY4RNPY1RNPY2RNPY5RC5AR1 | |
| SCHEMBL30851295 | 0.98 | NPY4R (0.52) | NPY4RNPY1RNPY2RNPY5RC5AR1 | |
| SCHEMBL29965839 | 0.95 | NPY4R (0.46) | NPY4RNPY1RNPY2RNPY5RC5AR1 | |
| SCHEMBL9551329 | 0.93 | C5AR1 (0.47) | NPY4RNPY1RNPY2RNPY5RC5AR1 | |
| SCHEMBL9551332 | 0.93 | C5AR1 (0.46) | NPY4RNPY1RNPY2RNPY5RC5AR1 | |
| SCHEMBL29659741 | 0.92 | NPY4R (0.47) | NPY4RNPY1RNPY2RNPY5RC5AR1 | |
| SCHEMBL31567997 | 0.92 | NPY4R (0.52) | NPY4RNPY1RNPY2RNPY5RGLP1R | |
| SCHEMBL31567999 | 0.92 | NPY4R (0.52) | NPY4RNPY1RNPY2RNPY5RGLP1R | |
| SCHEMBL31568000 | 0.92 | NPY4R (0.52) | NPY4RNPY1RNPY2RNPY5RGLP1R | |
| SCHEMBL30645272 | 0.92 | NPY4R (0.49) | NPY4RNPY1RNPY2RNPY5RC5AR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040253655-A1 | Immunoassay for use in detection high blood pressure; immunodiagnostics | SHINOGI SEIYAKU KABUSHIKI KAISHA | 2004-12-16 | — | — | US | claimed |
| US-6677124-B2 | NUCLEOTIDE SEQUENCES FOR USE IN THE DIAGNOSIS AND TREATMENT OF HYPERTENSION, HEART, AND KIDNEY DEFECTS | SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) | 2004-01-13 | — | — | US | claimed |
| US-20020025559-A1 | Monoclonal antibody recognizing C-terminus of hBNP | SHIONOGI SEIYAKU KABUSHIKI KAISHA | 2002-02-28 | — | — | US | claimed |
| EP-4591934-A2 | VARIANTS OF C-TYPE NATRIURETIC PEPTIDE | BioMarin Pharmaceutical Inc. (US) | 2025-07-30 | — | — | EP | disclosed |
| EP-4523749-A2 | VARIANTS OF C-TYPE NATRIURETIC PEPTIDE | BioMarin Pharmaceutical Inc. (US) | 2025-03-19 | — | — | EP | disclosed |
| US-12214015-B2 | Use of c-type natriuretic peptide variants to treat osteoarthritis | BIOMARIN PHARMACEUTICAL INC. (US) | 2025-02-04 | — | — | US | disclosed |
| EP-4029512-A1 | VARIANTS OF C-TYPE NATRIURETIC PEPTIDE | BioMarin Pharmaceutical Inc. (US) | 2022-07-20 | — | — | EP | disclosed |
| EP-4019038-A2 | USE OF C-TYPE NATRIURETIC PEPTIDE VARIANTS TO TREAT OSTEOARTHRITIS | BioMarin Pharmaceutical Inc. (US) | 2022-06-29 | — | — | EP | disclosed |
| US-20220160836-A1 | USE OF C-TYPE NATRIURETIC PEPTIDE VARIANTS TO TREAT OSTEOARTHRITIS | BIOMARIN PHARMACEUTICAL INC. | 2022-05-26 | — | — | US | disclosed |