Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 3/20 | 0.46 |
| ▸ | FNTB | P49356 | 3/20 | 0.46 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.41 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7086288 | 0.95 | FNTA (0.46) | FNTAFNTBPGGT1B | |
| SCHEMBL6711047 | 0.91 | GAA (0.50) | FNTAFNTBPGGT1BKCNA5GAA | |
| SCHEMBL6711073 | 0.90 | FNTA (0.50) | FNTAFNTBPGGT1B | |
| SCHEMBL6708752 | 0.90 | FNTA (0.46) | FNTAFNTBPGGT1BMAPT | |
| SCHEMBL6709665 | 0.89 | FNTA (0.49) | FNTAFNTBPGGT1BGAA | |
| SCHEMBL6712608 | 0.88 | FNTA (0.52) | FNTAFNTBPGGT1BLMNAGAA | |
| SCHEMBL6712710 | 0.87 | FNTA (0.47) | FNTAFNTBMAPTALDH1A1 | |
| SCHEMBL6708713 | 0.87 | FNTA (0.47) | FNTAFNTBPGGT1B | |
| SCHEMBL6712790 | 0.87 | FNTA (0.50) | FNTAFNTBPGGT1B | |
| SCHEMBL6711221 | 0.84 | FNTA (0.46) | FNTAFNTBPGGT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040092524-A1 | Novel aminophenyl piperazine or aminophenyl piperidine derivatives inhibiting prenyl transferase proteins and method for preparing same | PIERRE FABRE MEDICAMENT (FR) | 2004-05-13 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040092524-A1 | Novel aminophenyl piperazine or aminophenyl piperidine derivatives inhibiting prenyl transferase proteins and method for preparing same | CBR3, CBR1, HCCS | FNTA 194/4885FNTB 48/4885PGGT1B 1175/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.