SCHEMBL6712633

SCHEMBL6712633

[CH2]CCC=N

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2349561 0.77
SCHEMBL6900089 0.72
SCHEMBL875851 0.67
SCHEMBL4421289 0.64
SCHEMBL5984389 0.64
SCHEMBL944499 0.64
SCHEMBL9179105 0.64
SCHEMBL4251139 0.64
SCHEMBL3860878 0.62
SCHEMBL4142464 0.61

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 95 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117363186-B Water-based non-stick paint and preparation method thereof 广东日东工具有限公司 2024-04-19 CN claimed
CN-117467317-A Water-based varnish composition and preparation method and application thereof 广州立邦涂料有限公司 2024-01-30 CN claimed
CN-117363186-A Water-based non-stick paint and preparation method thereof 广东日东工具有限公司 2024-01-09 CN claimed
CN-110358447-B Single-component gold stamping coating and preparation method and application thereof 重庆韩拓科技有限公司 2021-10-08 CN claimed
CN-112724868-A Insulating dielectric composite film material and preparation method and application thereof 深圳先进技术研究院 2021-04-30 CN claimed
CN-112266695-A Ultrathin powder coating 湖南连心科技有限公司 2021-01-26 CN claimed
CN-111363432-A Low-temperature curing yellowing-resistant energy-saving gloss oil and preparation method and application thereof 佛山市儒林化工有限公司 2020-07-03 CN claimed
WO-2017157662-A1 POROUS THIN FILM MEMBRANE, METHOD FOR PRODUCING SAME AND POSSIBLE USES Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2017-09-21 WO claimed
EP-3219381-A1 POROUS THIN-FILM MEMBRANE, METHOD FOR THEIR PREPARATION AND USAGE OPTIONS Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2017-09-20 EP claimed
CN-103237801-A Quinoline or quinazoline derivatives having apoptosis-inducing activity on cells HANMI HOLDINGS CO LTD 2013-08-07 CN claimed
CN-102731413-A Urea compound and its preparation method, intermediate and use SHANGHAI INST PHARM INDUSTRY 2012-10-17 CN claimed
CN-102325763-A Sulfamides as TRPM8 modulators JANSSEN PHARMACEUTICA NV 2012-01-18 CN claimed
CN-101765602-A Derivatives of 6-cycloamino-3- (pyridin-4-yl) imidazo [1,2-b ] pyridazine, preparation thereof and therapeutic use thereof SANOFI AVENTIS 2010-06-30 CN claimed
CN-1244567-C Process for selectively protecting baccatin derivative and its application in synthesizing tartrialkane PHARMACOLOGY ENGINEERING RES S (FR) 2006-03-08 CN claimed
CN-1090625-C Method for selectively protecting baccatin derivatives and use thereof in synthesis of taxanes SERIPHARM (FR) 2002-09-11 CN claimed
CN-1356326-A Process for selectively protecting baccatin derivative and its application in synthesizing tartrialkane PHARMACOLOGY ENGINEERING RES S (FR) 2002-07-03 CN claimed
CN-1344274-A Pyroglutamic acid derivatives and related compounds that inhibit leukocyte adhesion mediated by VLA-4 ELAN PHARM INC (US) 2002-04-10 CN claimed
CN-1340058-A Compounds that inhibit leukocyte adhesion mediated by VLA-4 ELAN PHARM INC (US) 2002-03-13 CN claimed
CN-1206412-A Method for selectively protecting baccatin derivatives and use thereof in taxane synthesis SERIPHARM (FR) 1999-01-27 CN claimed
CN-117363186-B Water-based non-stick paint and preparation method thereof 广东日东工具有限公司 2024-04-19 CN disclosed
CN-117467317-A Water-based varnish composition and preparation method and application thereof 广州立邦涂料有限公司 2024-01-30 CN disclosed
CN-117363186-A Water-based non-stick paint and preparation method thereof 广东日东工具有限公司 2024-01-09 CN disclosed
CN-112680052-B Anti-reflective coating composition and application thereof 上海飞凯材料科技股份有限公司 2022-06-28 CN disclosed
CN-110591044-B High-physical-property low-fogging waterborne surface layer polyurethane resin and preparation method thereof 浙江华峰合成树脂有限公司 2022-01-14 CN disclosed
CN-111363432-B Low-temperature curing yellowing-resistant energy-saving gloss oil and preparation method and application thereof 佛山市儒林化工有限公司 2021-11-23 CN disclosed
CN-113667117-A Preparation method of water-soluble polyaniline, water-soluble polyaniline-containing high-temperature conductive primer for glass fiber reinforced plastics and preparation method of water-soluble polyaniline-containing water-soluble high-temperature conductive primer 清远市实创涂料科技有限公司 2021-11-19 CN disclosed
CN-110358447-B Single-component gold stamping coating and preparation method and application thereof 重庆韩拓科技有限公司 2021-10-08 CN disclosed
CN-112724868-A Insulating dielectric composite film material and preparation method and application thereof 深圳先进技术研究院 2021-04-30 CN disclosed
CN-112680052-A Anti-reflective coating composition and application thereof 上海飞凯光电材料股份有限公司 2021-04-20 CN disclosed
CN-112266695-A Ultrathin powder coating 湖南连心科技有限公司 2021-01-26 CN disclosed
CN-111363432-A Low-temperature curing yellowing-resistant energy-saving gloss oil and preparation method and application thereof 佛山市儒林化工有限公司 2020-07-03 CN disclosed
CN-110591044-A High-physical-property low-fogging waterborne surface layer polyurethane resin and preparation method thereof 浙江华峰合成树脂有限公司 2019-12-20 CN disclosed
WO-2017157662-A1 POROUS THIN FILM MEMBRANE, METHOD FOR PRODUCING SAME AND POSSIBLE USES Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2017-09-21 WO disclosed
EP-3219381-A1 POROUS THIN-FILM MEMBRANE, METHOD FOR THEIR PREPARATION AND USAGE OPTIONS Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2017-09-20 EP disclosed
CN-104169376-A Metal pigment- and solvent-containing pigment pastes, and use thereof for producing effect-producing solvent-containing coating materials BASF COATINGS GMBH 2014-11-26 CN disclosed
CN-103342696-A Substituted dihydropyrazolon for treating cardiovascular and haematological diseases BAYER HEALTHCARE AG 2013-10-09 CN disclosed
CN-101631785-B Substituted dihydropyrazolones for the treatment of cardiovascular and hematological disorders BAYER IP GMBH 2013-08-21 CN disclosed
CN-103237801-A Quinoline or quinazoline derivatives having apoptosis-inducing activity on cells HANMI HOLDINGS CO LTD 2013-08-07 CN disclosed
CN-101918368-B Method for improving the hydrolysis stability of ionic liquids BASF SE 2013-04-24 CN disclosed
CN-102844320-A Heterocyclic compounds TAKEDA PHARMACEUTICAL 2012-12-26 CN disclosed
CN-102731413-A Urea compound and its preparation method, intermediate and use SHANGHAI INST PHARM INDUSTRY 2012-10-17 CN disclosed
CN-102648199-A Piperidine compound and use thereof ASTRAZENECA AB 2012-08-22 CN disclosed
CN-101511729-B Templated metal oxide particles and methods of making 3M INNOVATIVE PROPERTIES CO 2012-08-08 CN disclosed
CN-102574801-A Substituted aminopropionic acid derivatives as enkephalinase inhibitors NOVARTIS AG 2012-07-11 CN disclosed
CN-101155856-B Templated metal particles in cross-linked dendrimers in nucleus and methods of making 3M INNOVATIVE PROPERTIES CO 2012-06-13 CN disclosed
CN-102325763-A Sulfamides as TRPM8 modulators JANSSEN PHARMACEUTICA NV 2012-01-18 CN disclosed
CN-102304075-A Inhibitors of viral replication INTERMUNE INC 2012-01-04 CN disclosed
CN-102066339-A 2, 6-diamino-pyrimidin-5-yl-carboxamides as SYK or JAK protein kinase inhibitors PORTOLA PHARM INC 2011-05-18 CN disclosed
CN-1922139-B Bicyclic amide derivatives KYORIN SEIYAKU KK 2010-12-29 CN disclosed
CN-101918368-A Method for improving the hydrolysis stability of ionic liquids BASF SE 2010-12-15 CN disclosed
CN-101765602-A Derivatives of 6-cycloamino-3- (pyridin-4-yl) imidazo [1,2-b ] pyridazine, preparation thereof and therapeutic use thereof SANOFI AVENTIS 2010-06-30 CN disclosed
CN-1938307-B 9-substituted 8-oxoadenines DAINIPPON SUMITOMO PHARMA CO 2010-06-16 CN disclosed
CN-101704804-A Semisynthesis process for the preparation of 10-deacetyl-n-debenzoyl-paclitaxel INDENA SPA 2010-05-12 CN disclosed
CN-100584836-C Semi-synthetic process for the preparation of 10-deacetyl-N-debenzoyl-taxol INDENA SPA 2010-01-27 CN disclosed
CN-101631785-A Substituted dihydropyrazolones for the treatment of cardiovascular and hematological disorders BAYER SCHERING PHARMA AG 2010-01-20 CN disclosed
CN-101622252-A Substituted triazoles useful as AXL inhibitors RIGEL PHARMACEUTICALS INC 2010-01-06 CN disclosed
CN-101617055-A Carry out the method that enzymically hydrolyse prepares glucose by use being contained the polyatom anion ion liquid from the Mierocrystalline cellulose that the material of lignocellulose-containing obtains BASF SE 2009-12-30 CN disclosed
CN-101589153-A Method for producing glucose by enzymatic hydrolysis of cellulose that can be pretreated with an ionic liquid containing a polyatomic anion BASF SE (DE) 2009-11-25 CN disclosed
CN-101511729-A Templated metal oxide particles and methods of making 3M INNOVATIVE PROPERTIES CO (US) 2009-08-19 CN disclosed
CN-101501006-A Pyridone and pyridazinone derivatives as poly (ADP-ribose) polymerase (PARP) inhibitors ANGELETTI P IST RICHERCHE BIO (IT) 2009-08-05 CN disclosed
CN-101304976-A Inhibitors of viral replication INTERMUNE INC (US) 2008-11-12 CN disclosed
CN-101300291-A Templated semiconductor particles and methods of making 3M INNOVATIVE PROPERTIES CO (US) 2008-11-05 CN disclosed
CN-100422174-C Piperidinyl-quinazoline derivatives as tyrosine kinase inhibitors ASTRAZENECA AB (SE) 2008-10-01 CN disclosed
CN-101273031-A Imidazolyl-pyrimidine compounds for use in the treatment of proliferative disorders ASTRAZENECA AB (SE) 2008-09-24 CN disclosed
CN-101208331-A Quinazoline derivatives as inhibitors of EGF and/or ERBB2 tyrosine kinases ASTRAZENECA AB (SE) 2008-06-25 CN disclosed
CN-101208332-A Quinazoline derivatives as inhibitors of egf and/or erbb2 receptor tyrosine kinase ASTRAZENECA AB (SE) 2008-06-25 CN disclosed
CN-101048395-A Semi-synthetic process for the preparation of 10-deacetyl-N-debenzoyl-taxol INDENA SPA (IT) 2007-10-03 CN disclosed
CN-100339376-C Nitrogen-containing aromatic ring derivatives EISAI CO LTD (JP) 2007-09-26 CN disclosed
CN-1993349-A Quinazoline derivatives as ERBB receptor tyrosine kinases ASTRAZENECA AB (SE) 2007-07-04 CN disclosed
CN-1960975-A Substituted pyridones as poly (ADP-ribose) polymerase (PARP) inhibitors AVENTIS PHARMA INC (US) 2007-05-09 CN disclosed
CN-1938307-A 9-substituted 8-oxoadenines DAINIPPON SUMITOMO PHARMA CO (JP) 2007-03-28 CN disclosed
CN-1856487-A Piperidyl-quinazoline derivatives as tyrosine kinase inhibitors ASTRAZENECA AB (SE) 2006-11-01 CN disclosed
CN-1244567-C Process for selectively protecting baccatin derivative and its application in synthesizing tartrialkane PHARMACOLOGY ENGINEERING RES S (FR) 2006-03-08 CN disclosed
CN-1243745-C Process for selectively protecting baccatin derivative and its application in synthesizing tartrialkane PHARMACOLOGY ENGINEERING RES S (FR) 2006-03-01 CN disclosed
CN-1708579-A Use of metal complexes as catalysts for oxidation with molecular oxygen or air CIBA SC HOLDING AG (CH) 2005-12-14 CN disclosed
CN-1678607-A Nitrogen-containing aromatic ring derivatives EISAI CO LTD (JP) 2005-10-05 CN disclosed
CN-1195773-C Pyroglutamic acid derivatives and related compounds that inhibit leukocyte adhesion mediated by VLA-4 ELAN PHARM INC (US) 2005-04-06 CN disclosed
CN-1185250-C Compounds that inhibit leukocyte adhesion mediated by VLA-4 ELAN PHARM INC (US) 2005-01-19 CN disclosed
US-20040180947-A1 hypoglycemic activity or phoshodiesterase-V inhibitory activity; prophylaxis and treatment of impaired glucose tolerance disorder, diabetes (e.g., type II diabetes), diabetic complications FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2004-09-16 US disclosed
CN-1090625-C Method for selectively protecting baccatin derivatives and use thereof in synthesis of taxanes SERIPHARM (FR) 2002-09-11 CN disclosed
CN-1356325-A Process for selectively protecting baccatin derivative and its application in synthesizing tartrialkane PHARMACOLOGY ENGINEERING RES S (FR) 2002-07-03 CN disclosed
CN-1356326-A Process for selectively protecting baccatin derivative and its application in synthesizing tartrialkane PHARMACOLOGY ENGINEERING RES S (FR) 2002-07-03 CN disclosed
CN-1344274-A Pyroglutamic acid derivatives and related compounds that inhibit leukocyte adhesion mediated by VLA-4 ELAN PHARM INC (US) 2002-04-10 CN disclosed
CN-1340058-A Compounds that inhibit leukocyte adhesion mediated by VLA-4 ELAN PHARM INC (US) 2002-03-13 CN disclosed
US-5939558-A HERBICIDES, DEFOLIANTS BASF AKTIENGESELLSCHAFT (DE) 1999-08-17 US disclosed
CN-1206412-A Method for selectively protecting baccatin derivatives and use thereof in taxane synthesis SERIPHARM (FR) 1999-01-27 CN disclosed
CN-1171394-A New urea derivatives, their preparation and their therapeutic and prophylactic use SANKYO CO (JP) 1998-01-28 CN disclosed
EP-0777654-A1 N-PHENYLTETRAHYDROINDAZOLES, THEIR PREPARATION, AND THEIR USE AS CROP PROTECTION AGENTS BASF AKTIENGESELLSCHAFT (DE) 1997-06-11 EP disclosed
WO-1996006830-A1 N-PHENYLTETRAHYDROINDAZOLES, THEIR PREPARATION, AND THEIR USE AS CROP PROTECTION AGENTS BASF AKTIENGESELLSCHAFT (DE) 1996-03-07 WO disclosed
EP-0661266-A1 Substituted cyclic amine compounds as 5HT2 antagonists TOA EIYO LTD. (JP) 1995-07-05 EP disclosed
CN-1068108-A Be used to prepare the aza cyclo-butanone derivatives of carbapenem antibiotics SANKYO CO (JP) 1993-01-20 CN disclosed
EP-0360079-A1 Tricyclic compounds, processes for their preparation and pharmaceutical compositions comprising them FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1990-03-28 EP disclosed
US-4698339-A BETA-LACTAMASE INHIBITORS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1987-10-06 US disclosed
EP-0137403-A2 Carbapenems, their production and use Takeda Chemical Industries, Ltd. (JP) 1985-04-17 EP disclosed
EP-0069373-A1 (5R, 6R)-Penem compounds, their production and use Takeda Chemical Industries, Ltd. (JP) 1983-01-12 EP disclosed
EP-0069373-A1 (5R, 6R)-Penem compounds, their production and use Takeda Chemical Industries, Ltd. (JP) 1983-01-12 EP disclosed