SCHEMBL6712781

SCHEMBL6712781

Cn1cccc1C(=O)N1CCN(c2ccc(N(Cc3cncn3Cc3ccc(C#N)cc3)C(=O)c3ccccc3)cc2)CC1

nearest known ligand 0.73

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
FNTA P49354 5/20 0.50
FNTB P49356 5/20 0.50
USP2 O75604 2/20 0.46
CYP2C19 P33261 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
PGGT1B P53609 3/20 0.46
MEN1 O00255 1/20 0.43
CYP1A2 P05177 1/20 0.43
CYP3A4 P08684 1/20 0.43
KMT2A Q03164 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6711099 0.86 FNTA (0.48) FNTAFNTBPGGT1B
SCHEMBL6712743 0.85 FNTA (0.46) FNTAFNTBPGGT1B
SCHEMBL6712621 0.85 FNTA (0.48) FNTAFNTBPGGT1B
SCHEMBL6709731 0.85 FNTA (0.47) FNTAFNTBPGGT1B
SCHEMBL6712609 0.84 FNTA (0.48) FNTAFNTBPGGT1B
SCHEMBL6708786 0.84 FNTA (0.48) FNTAFNTBPGGT1B
SCHEMBL6710999 0.84 MAPKAPK2 (0.55)
SCHEMBL6711334 0.84 FNTA (0.47) FNTAFNTBPGGT1B
SCHEMBL6708647 0.84 FNTA (0.47) FNTAFNTBPGGT1B
SCHEMBL6709677 0.84 MAPT (0.48) FNTAFNTBUSP2SMN1; SMN2PGGT1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040092524-A1 Novel aminophenyl piperazine or aminophenyl piperidine derivatives inhibiting prenyl transferase proteins and method for preparing same PIERRE FABRE MEDICAMENT (FR) 2004-05-13 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040092524-A1 Novel aminophenyl piperazine or aminophenyl piperidine derivatives inhibiting prenyl transferase proteins and method for preparing same CBR3, CBR1, HCCS FNTA 194/4885FNTB 48/4885USP2 2680/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.