Known targets — ChEMBL curated mechanism
CHRM1DRD2DRD3DRD4HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR2APDE3ASIGMAR1
The experimentally established mechanism targets of Lactic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lactic Acid SCHEMBL1517852 | 1.00 | TP53 (0.85) | — | |
| Lactic Acid SCHEMBL21145267 | 0.96 | — | — | |
| Lactic Acid SCHEMBL27901579 | 0.92 | — | — | |
| Lactic Acid SCHEMBL26674102 | 0.92 | TP53 (0.85) | — | |
| D-Lactic Acid SCHEMBL14947 | 0.92 | — | — | |
| L-Lactic Acid SCHEMBL13165963 | 0.92 | — | — | |
| Lactic Acid SCHEMBL5189465 | 0.92 | TP53 (1.00) | — | |
| Lactic Acid SCHEMBL9066423 | 0.92 | TP53 (1.00) | — | |
| Lactic Acid SCHEMBL180386 | 0.92 | TP53 (1.00) | — | |
| D-Lactic Acid SCHEMBL4371722 | 0.92 | TP53 (1.00) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 643 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104661639-B | Novel pharmaceutical compositions for the treatment of fungal infections | 莫贝里制药公司 | 2019-06-28 | — | — | CN | claimed |
| CN-109394743-A | Novel pharmaceutical compositions for the treatment of fungal infections | 莫贝里制药公司 | 2019-03-01 | — | — | CN | claimed |
| CN-109181837-A | A kind of aqueous lubricating oil and its preparation method and application | 南京巨鲨显示科技有限公司 | 2019-01-11 | — | — | CN | claimed |
| CN-108627647-A | A kind of detection of posttranslational modification proteomics and quantitative approach | 四川大学 | 2018-10-09 | — | — | CN | claimed |
| CN-108135860-A | Transdermal adhesive compositions containing poorly soluble therapeutic agents | 考里安国际公司 | 2018-06-08 | — | — | CN | claimed |
| CN-104135954-B | Film and manufacture method | 新特斯有限责任公司 | 2017-11-07 | — | — | CN | claimed |
| CN-106479278-A | Self-cleaning type air cleaning powdery paints and preparation method thereof | 金福兴 | 2017-03-08 | — | — | CN | claimed |
| CN-106478768-A | A kind of N- phosphorylation peptide gathering method | 中国科学院大连化学物理研究所 | 2017-03-08 | — | — | CN | claimed |
| CN-103459473-B | The manufacture method of polyacrylic acid (salt) water-absorbent resin powder | NIPPON SHOKUBAI CO.,LTD. (JP) | 2016-04-13 | — | — | CN | claimed |
| CN-102311863-B | Method for wafer dicing and composition useful thereof | AIR PROD & CHEM | 2015-06-24 | — | — | CN | claimed |
| CN-1972698-A | Beta-hydroxy short-medium chain fatty acid polymers | EARTHUS INC (JP) | 2007-05-30 | — | — | CN | claimed |
| CN-1950474-A | Adhesive for skin patch and preparation method thereof | SHOWA DENKO KK (JP) | 2007-04-18 | — | — | CN | claimed |
| CN-1863572-A | Method and device for enhancing transdermal agent flux | JOHNSON & JOHNSON (US) | 2006-11-15 | — | — | CN | claimed |
| CN-1863571-A | Method and apparatus for enhancing transdermal flux of pharmaceutical agents | JOHNSON & JOHNSON (US) | 2006-11-15 | — | — | CN | claimed |
| CN-1260202-C | Method for setting liquid level gauge | MITSUBISHI CHEM CORP (JP) | 2006-06-21 | — | — | CN | claimed |
| CN-1231270-C | Surface-modified implant and method for producing same | STRAUMANN INST AG (CH) | 2005-12-14 | — | — | CN | claimed |
| CN-1610655-A | Method for producing acrylic acid compound | MITSUBISHI CHEM CORP (JP) | 2005-04-27 | — | — | CN | claimed |
| CN-1610072-A | Method of second step polishing in copper CMP with a polishing fluid containing no oxidizing agent | CMP ROHM AND HAAS ELECTRONIC M (US) | 2005-04-27 | — | — | CN | claimed |
| CN-1562948-A | Method for producing acrylic acid compound | MITSUBISHI CHEM CORP (JP) | 2005-01-12 | — | — | CN | claimed |
| CN-1138809-C | Polyester | 施瓦茨制药有限公司 | 2004-02-18 | — | — | CN | claimed |