Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | PTPRF | P10586 | 1/20 | 0.49 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA4 | P22748 | 1/20 | 0.48 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1851099 | 0.98 | CHRM2 (0.55) | CHRM2CYP1A2CYP2C9CYP2C19PTPRF | |
| SCHEMBL3155876 | 0.88 | CYP1A2 (0.64) | CHRM2CYP1A2CYP2C9CYP2C19PTPRF | |
| SCHEMBL628651 | 0.86 | CHRM2 (0.72) | CHRM2CYP2C19PTPRFPTPN2PTPN1 | |
| SCHEMBL1041853 | 0.79 | MEN1 (0.69) | CHRM2CYP1A2CYP2C9CYP2C19PTPRF | |
| SCHEMBL11597593 | 0.78 | CHRM2 (0.79) | CHRM2CYP2C19PTPRFPTPN2PTPN1 | |
| SCHEMBL6714936 | 0.78 | CYP2C19 (0.51) | CYP1A2CYP2C9CYP2C19PTPRFPTPN2 | |
| SCHEMBL11816248 | 0.77 | CYP1A2 (0.64) | CHRM2CYP1A2CYP2C9CYP2C19PTPRF | |
| SCHEMBL18633755 | 0.77 | CHRM2 (0.62) | CHRM2CYP2C19PTPRFPTPN2PTPN1 | |
| SCHEMBL31163970 | 0.77 | POLB (0.58) | CYP1A2CYP2C9CYP2C19MAPTMEN1 | |
| Hydrochloric Acid SCHEMBL27921640 | 0.76 | MEN1 (0.66) | CHRM2CYP1A2CYP2C9CYP2C19MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1470102-A1 | SUBSTITUTED METHYLENE AMIDE DERIVATIVES AS MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPS) | Applied Research Systems ARS Holding N.V. (AN) | 2004-10-27 | — | — | EP | disclosed |
| WO-2003064376-A1 | SUBSTITUTED METHYLENE AMIDE DERIVATIVES AS MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPS) | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2003-08-07 | — | — | WO | disclosed |