Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL45165 | 0.82 | — | — | |
| Ethylene Glycol SCHEMBL27751387 | 0.79 | SLC22A6 (0.43) | SLC22A6TDP1SMN1; SMN2GABRR1LMNA | |
| SCHEMBL1273566 | 0.79 | SLC22A6 (0.35) | SLC22A6TDP1SMN1; SMN2GABRR1LMNA | |
| SCHEMBL28001442 | 0.79 | — | — | |
| SCHEMBL27437876 | 0.79 | — | — | |
| SCHEMBL28325056 | 0.79 | — | — | |
| SCHEMBL29180593 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL11213722 | 0.79 | — | — | |
| Methyl Alcohol SCHEMBL3561710 | 0.76 | — | — | |
| Methylene Chloride SCHEMBL9525414 | 0.76 | SLC22A6 (0.45) | SLC22A6TDP1SMN1; SMN2GABRR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040072222-A1 | Peptide analogues of myelin basic protein epitopes in the treatment of experimental autoimmune encephalomyelitis (eae) and multiple sclerosis (ms) | MATSOUKAS JOHN (GR) | 2004-04-15 | — | — | US | disclosed |
| EP-1370582-A1 | PEPTIDE ANALOGUES OF MYELIN BASIC PROTEIN EPITOPES IN THE TREATMENT OF EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS (EAE) AND MULTIPLE SCLEROSIS (MS) | Matsoukas, John (GR) | 2003-12-17 | — | — | EP | disclosed |
| WO-2002077025-A1 | PEPTIDE ANALOGUES OF MYELIN BASIC PROTEIN EPITOPES IN THE TREATMENT OF EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS (EAE) AND MULTIPLE SCLEROSIS (MS) | MATSOUKAS JOHN (GR) | 2002-10-03 | — | — | WO | disclosed |