Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.55 |
| ▸ | MAPT | P10636 | 7/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 6/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | KDR | P35968 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6719344 | 0.87 | MEN1 (0.53) | MEN1KMT2AMAPTHPGDCYP1A2 | |
| SCHEMBL6718190 | 0.86 | MEN1 (0.58) | MEN1KMT2AMAPTHPGDCYP1A2 | |
| SCHEMBL6726369 | 0.85 | MEN1 (0.61) | MEN1KMT2AMAPTHPGDCYP1A2 | |
| SCHEMBL6720022 | 0.85 | MEN1 (0.63) | MEN1KMT2AMAPTHPGDCYP1A2 | |
| SCHEMBL6715561 | 0.84 | MEN1 (0.56) | MEN1KMT2AMAPTHPGDCYP1A2 | |
| SCHEMBL6719896 | 0.84 | MEN1 (0.64) | MEN1KMT2AMAPTHPGDCYP1A2 | |
| SCHEMBL6726598 | 0.83 | MEN1 (0.59) | MEN1KMT2AMAPTHPGDCYP1A2 | |
| SCHEMBL6726683 | 0.81 | MEN1 (0.61) | MEN1KMT2AMAPTHPGDCYP1A2 | |
| SCHEMBL6726774 | 0.81 | MEN1 (0.61) | MEN1KMT2AMAPTHPGDCYP1A2 | |
| SCHEMBL6719099 | 0.81 | MEN1 (0.66) | MEN1KMT2AMAPTHPGDCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040152741-A1 | Arylglycine derivatives and their use as glycine transport inhibitors | NPS ALLELIX CORPORATION (CA) | 2004-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040152741-A1 | Arylglycine derivatives and their use as glycine transport inhibitors | SLC1A2, SLC1A1, SLC7A11 | MEN1 2822/4885KMT2A 1656/4885MAPT 694/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.