SCHEMBL6716038

SCHEMBL6716038

CCOC(Cc1ccc(OCCOC2c3ccc(CC)cc3C=Cc3ccc(CCc4ccccc4)cc32)cc1)C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 18/20 0.50
PPARG P37231 16/20 0.50
PPARD Q03181 8/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6719004 0.97 PPARA (0.53) PPARAPPARGPPARD
SCHEMBL6717942 0.95 PPARA (0.50) PPARAPPARGPPARD
SCHEMBL6724182 0.94 PPARA (0.49) PPARAPPARGPPARD
SCHEMBL6715620 0.94 PPARA (0.51) PPARAPPARGPPARD
SCHEMBL6715684 0.94 PPARA (0.43) PPARAPPARGPPARD
SCHEMBL6724527 0.93 PPARA (0.50) PPARAPPARGPPARD
SCHEMBL6719675 0.93 PPARA (0.50) PPARAPPARGPPARD
SCHEMBL6719706 0.93 PPARA (0.47) PPARAPPARGPPARD
SCHEMBL6717366 0.93 PPARA (0.47) PPARAPPARGPPARD
SCHEMBL6717819 0.93 PPARA (0.55) PPARAPPARGPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20010031764-A1 Compounds useful in the treatment of conditions mediated by peroxisome proliferator-activated receptors(PPAR) JEPPESEN LONE (DK) 2001-10-18 US claimed
US-20010031786-A1 Compounds useful in the treatment of conditions mediated by peroxisome proliferator-activated receptors (PPAR) JEPPESEN LONE (DK) 2001-10-18 US claimed
EP-1123269-A1 NEW COMPOUNDS, THEIR PREPARATION AND USE NOVO NORDISK A/S (DK) 2001-08-16 EP claimed
WO-2000023417-A1 NEW COMPOUNDS, THEIR PREPARATION AND USE NOVO NORDISK A/S (DK) 2000-04-27 WO claimed
US-20040229899-A1 Compounds useful in the treatment of conditions mediated by peroxisome proliferator-activated receptors (PPAR) JEPPESEN LONE (DK) 2004-11-18 US disclosed
US-6602901-B2 Antidiabetic agents, obesity NOVO NORDISK A/S (DK) 2003-08-05 US disclosed
US-20010031786-A1 Compounds useful in the treatment of conditions mediated by peroxisome proliferator-activated receptors (PPAR) JEPPESEN LONE (DK) 2001-10-18 US disclosed
EP-1123269-A1 NEW COMPOUNDS, THEIR PREPARATION AND USE NOVO NORDISK A/S (DK) 2001-08-16 EP disclosed
US-6248781-B1 ANTIDIABETIC AGENTS; DIETETICS NOVO NORDISK A/S (DK) 2001-06-19 US disclosed
WO-2000023417-A1 NEW COMPOUNDS, THEIR PREPARATION AND USE NOVO NORDISK A/S (DK) 2000-04-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010031786-A1 Compounds useful in the treatment of conditions mediated by peroxisome proliferator-activated receptors (PPAR) PPARG, PPARA, PPARD PPARA 2/4885PPARG 1/4885PPARD 3/4885
US-20010031764-A1 Compounds useful in the treatment of conditions mediated by peroxisome proliferator-activated receptors(PPAR) PPARG, PPARA, PPARD PPARA 2/4885PPARG 1/4885PPARD 3/4885
US-20040229899-A1 Compounds useful in the treatment of conditions mediated by peroxisome proliferator-activated receptors (PPAR) PPARG, PPARA, PPARD PPARA 2/4885PPARG 1/4885PPARD 3/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.