Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR3 | P32745 | 8/20 | 0.69 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | CCKBR | P32239 | 1/20 | 0.43 |
| ▸ | PDE5A | O76074 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6716252 | 1.00 | SSTR3 (0.69) | SSTR3KCNH2HDAC1HDAC6MEN1 | |
| SCHEMBL6717600 | 0.77 | SSTR3 (0.65) | SSTR3KCNH2CYP2D6 | |
| SCHEMBL6717602 | 0.77 | SSTR3 (0.65) | SSTR3KCNH2CYP2D6 | |
| SCHEMBL1244098 | 0.77 | SSTR3 (0.44) | SSTR3KCNH2MEN1ALDH1A1KMT2A | |
| SCHEMBL3002454 | 0.76 | SSTR3 (0.73) | SSTR3KCNH2 | |
| SCHEMBL6713929 | 0.74 | MAPT (0.50) | SSTR3MEN1KMT2APDE5ADHODH | |
| SCHEMBL6713926 | 0.74 | MAPT (0.50) | SSTR3MEN1KMT2APDE5ADHODH | |
| SCHEMBL13244716 | 0.74 | SSTR3 (0.69) | SSTR3KCNH2 | |
| SCHEMBL3010196 | 0.74 | SSTR3 (0.50) | SSTR3KCNH2 | |
| SCHEMBL13244611 | 0.73 | SSTR3 (0.73) | SSTR3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040038970-A1 | Beta-carboline compounds | SOCIETE DE CONSEILS DE RECHERCHES ETD' APPLICATION SCIENTIFIQUES, S.A.S. A PARIS, FRANCE CORP. | 2004-02-26 | — | — | US | disclosed |
| US-6586445-B1 | Racemic mixtures of 1,2,3,4-tetra hydro-1-(4-methoxyphenyl)-3 -(4-phenyl-1H-imidazol-2-yl)-9H- pyrido(3,4-b)indole, which bind to somatostatin receptors and block sodium channel modulators; antidiabetic, antiinflammatory agents; diarrhea | Société de Conseils de Recherches et d'Applications Scientifiques, S.A.S. (FR) | 2003-07-01 | — | — | US | disclosed |
| EP-1086101-B1 | BETA-CARBOLINE COMPOUNDS | SOD CONSEILS RECH APPLIC (FR) | 2002-12-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040038970-A1 | Beta-carboline compounds | SCN1B, SCN2B, CACNA1B | SSTR3 49/4885KCNH2 78/4885HDAC1 1737/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.