Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.50 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.50 |
| ▸ | S1PR1 | P21453 | 10/20 | 0.45 |
| ▸ | S1PR3 | Q99500 | 10/20 | 0.45 |
| ▸ | S1PR2 | O95136 | 8/20 | 0.45 |
| ▸ | S1PR4 | O95977 | 5/20 | 0.45 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.39 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP12 | P39900 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1852068 | 0.92 | FFAR1 (0.49) | FFAR1FFAR4S1PR1S1PR3S1PR2 | |
| SCHEMBL1859815 | 0.92 | FFAR1 (0.49) | FFAR1FFAR4S1PR1S1PR3S1PR2 | |
| SCHEMBL4963278 | 0.92 | FFAR1 (0.49) | FFAR1FFAR4S1PR1S1PR3S1PR2 | |
| SCHEMBL4966912 | 0.92 | FFAR1 (0.49) | FFAR1FFAR4S1PR1S1PR3S1PR2 | |
| SCHEMBL1850763 | 0.92 | FFAR1 (0.49) | FFAR1FFAR4S1PR1S1PR3S1PR2 | |
| SCHEMBL1853554 | 0.83 | FFAR1 (0.46) | FFAR1FFAR4LMNAMMP2MMP12 | |
| SCHEMBL1853660 | 0.83 | FFAR1 (0.46) | FFAR1FFAR4LMNAMMP2MMP12 | |
| SCHEMBL1854388 | 0.83 | S1PR1 (0.50) | S1PR1S1PR3S1PR2S1PR4LPAR2 | |
| SCHEMBL1855128 | 0.83 | S1PR1 (0.50) | S1PR1S1PR3S1PR2S1PR4LPAR2 | |
| SCHEMBL1852885 | 0.82 | FFAR1 (0.45) | FFAR1FFAR4HRH3MMP2MMP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1470102-A1 | SUBSTITUTED METHYLENE AMIDE DERIVATIVES AS MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPS) | Applied Research Systems ARS Holding N.V. (AN) | 2004-10-27 | — | — | EP | disclosed |
| WO-2003064376-A1 | SUBSTITUTED METHYLENE AMIDE DERIVATIVES AS MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPS) | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2003-08-07 | — | — | WO | disclosed |