Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15511618 | 0.90 | NR1I2 (0.35) | RAF1NR1I2 | |
| SCHEMBL671749 | 0.77 | MEN1 (0.36) | RAF1 | |
| SCHEMBL669904 | 0.71 | RAF1 (0.43) | RAF1NR1I2 | |
| SCHEMBL675139 | 0.71 | NR1I2 (0.34) | RAF1NR1I2 | |
| SCHEMBL668933 | 0.71 | MEN1 (0.38) | RAF1NR1I2 | |
| SCHEMBL671251 | 0.69 | NR1I2 (0.34) | RAF1NR1I2 | |
| SCHEMBL675371 | 0.68 | CYP2E1 (0.53) | NR1I2 | |
| SCHEMBL669376 | 0.68 | CYP2E1 (0.53) | NR1I2 | |
| SCHEMBL669609 | 0.68 | MEN1 (0.38) | RAF1 | |
| SCHEMBL673731 | 0.68 | RAF1 (0.40) | RAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2606041-A2 | COMPOUNDS AND METHODS FOR THE TREATMENT OR PREVENTION OF FLAVIVIRIDAE VIRAL INFECTIONS | Vertex Pharmaceuticals Incorporated (US) | 2013-06-26 | — | — | EP | disclosed |
| WO-2012024363-A2 | COMPOUNDS AND METHODS FOR THE TREATMENT OR PREVENTION OF FLAVIVIRIDAE VIRAL INFECTIONS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2012-02-23 | — | — | WO | disclosed |