Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 20/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1251535 | 0.80 | PARP1 (0.45) | PARP1 | |
| SCHEMBL1252034 | 0.78 | PARP1 (0.44) | PARP1 | |
| Hydrochloric Acid SCHEMBL1252307 | 0.76 | PARP1 (0.41) | PARP1 | |
| Hydrochloric Acid SCHEMBL1252428 | 0.73 | PARP1 (0.40) | PARP1 | |
| SCHEMBL1249893 | 0.72 | PARP1 (0.50) | PARP1 | |
| SCHEMBL1252047 | 0.71 | PARP1 (0.39) | PARP1 | |
| SCHEMBL1252284 | 0.69 | TSHR (0.56) | PARP1 | |
| SCHEMBL1251951 | 0.67 | POLB (0.51) | PARP1 | |
| SCHEMBL19902540 | 0.63 | PARP1 (0.51) | PARP1 | |
| SCHEMBL1252318 | 0.62 | PARP1 (0.47) | PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1477175-A1 | FUSED PYRIDAZINE DERIVATIVE COMPOUNDS AND DRUGS CONTAINING THE COMPOUNDS AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2004-11-17 | — | — | EP | disclosed |