Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 3/20 | 0.40 |
| ▸ | CES1 | P23141 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.39 |
| ▸ | PPARG | P37231 | 6/20 | 0.39 |
| ▸ | PPARD | Q03181 | 6/20 | 0.39 |
| ▸ | PPARA | Q07869 | 6/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.39 |
| ▸ | TLR2 | O60603 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | FABP4 | P15090 | 2/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.39 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL673037 | 1.00 | TSHR (0.42) | TSHRTHRBCES2CES1ALDH1A1 | |
| SCHEMBL672641 | 1.00 | TSHR (0.42) | TSHRTHRBCES2CES1ALDH1A1 | |
| SCHEMBL674606 | 1.00 | TSHR (0.42) | TSHRTHRBCES2CES1ALDH1A1 | |
| SCHEMBL674840 | 1.00 | TSHR (0.42) | TSHRTHRBCES2CES1ALDH1A1 | |
| SCHEMBL672813 | 1.00 | TSHR (0.42) | TSHRTHRBCES2CES1ALDH1A1 | |
| SCHEMBL4481764 | 0.97 | TSHR (0.44) | TSHRTHRBCES2CES1ALDH1A1 | |
| SCHEMBL16243948 | 0.97 | TSHR (0.44) | TSHRTHRBCES2CES1ALDH1A1 | |
| SCHEMBL686906 | 0.97 | — | — | |
| SCHEMBL600688 | 0.97 | TSHR (0.44) | TSHRTHRBCES2CES1ALDH1A1 | |
| SCHEMBL6441968 | 0.97 | TSHR (0.44) | TSHRTHRBCES2CES1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120252979-A1 | Process for Producing Blends of Syndiotactic, 1,2-Polybutadiene and Rubbery Elastomers | RADEMACHER CHRISTINE (US) | 2012-10-04 | — | — | US | disclosed |
| US-8067503-B2 | Process for producing blends of syndiotactic, 1,2-polybutadiene and rubbery elastomers | BRIDGESTONE CORPORATION (JP) | 2011-11-29 | — | — | US | disclosed |
| US-20070161748-A1 | PROCESS FOR PRODUCING BLENDS OF SYNDIOTACTIC, 1,2-POLYBUTADIENE AND RUBBERY ELASTOMERS | BRIDGESTONE CORPORATION | 2007-07-12 | — | — | US | disclosed |
| US-20040242780-A1 | using a catalyst that is based on a chromium-containing compound, a hydrogen phosphite, and an organomagnesium compound, or a catalyst based on a molybdenum or iron-compound, a hydrogen phosphite and organoaluminum compound; tire sidewalls; obviates the need for high-temperature mixing | BRIDGESTONE CORPORATION (JP) | 2004-12-02 | — | — | US | disclosed |
| WO-2003040231-A1 | PROCESS FOR PRODUCING BLENDS OF SYNDIOTACTIC 1,2-POLYBUTADIENE AND RUBBERY ELASTOMERS | BRIDGESTONE CORPORATION (JP) | 2003-05-15 | — | — | WO | disclosed |
| US-6528588-B2 | Polymerization of 1,3-butadiene in the presence of a catalyst made of a chromium compound, a hydrogen phosphite, an organomagnesium compound, a molybdenum containing compound and an organoaluminum compound | BRIDGESTONE CORPORATION (JP) | 2003-03-04 | — | — | US | disclosed |
| US-6465585-B2 | REACTION PRODUCT OF A CHROMIUM CONTAINING COMPOUND, AN ORGANOMAGNESIUM COMPOUND AND A SILYL PHOSPHONATE | BRIDGESTONE CORPORATION (JP) | 2002-10-15 | — | — | US | disclosed |
| US-20020115558-A1 | CHROMIUM-BASED CATALYST COMPOSITION FOR PRODUCING CONJUGATED DIENE POLYMERS | BRIDGESTONE CORP. | 2002-08-22 | — | — | US | disclosed |
| US-20020037967-A1 | Process for producing blends of syndiotactic 1,2-polybutadiene and rubbery elastomers with a chromium-based catalyst system | BRIDGESTONE CORPORATION (JP) | 2002-03-28 | — | — | US | disclosed |
| US-6291591-B1 | PROVIDING MIXTURE OF RUBBER CEMENT AND 1,3-BUTADIENE; POLYMERIZING 1,3-BUTADIENE BY USING A CATALYST WHICH IS COMBINATION OF OR THE REACTION PRODUCT OF CHROMIUM COMPOUND, HYDROGEN PHOSPHITE, ORGANOMAGNESIUM COMPOUND | BRIDGESTONE CORPORATION (JP) | 2001-09-18 | — | — | US | disclosed |